ID | 83267 |
Author |
Kubo, Shin-ichi
Department of Legal Medicine, The University of Tokushima School of Medicine
Ogata, Mamoru
Department of Legal Medicine, Faculity of Medicine, Kagoshima University
Kitamura, Osamu
Department of Forensic Medicine, The Jikei University School of Medicine
Nakasono, Ichiro
Department of Legal medicine, Nagasaki University School of Medicine
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Keywords | tetralogy of Fallot
forensic pathology
cause of death
traffic accidental death
immunohistochemistry
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Content Type |
Journal Article
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Description | The case of a61-year-old male traffic accident victem with Tetralogy of Fallot (TOF) is reported. The autopsy revealed massive hemorrhages in the subcutaneous tissue, muscle, and subarachnoidal space. Furthermore, multiple fractures of ribs, sternum and thoracic vertebrae were observed. Histopathological examination revealed changes characteristic of trauma, such as acute lung congestion, acute renal cortical necrosis, and embolization in the lungs and kidney. These autopsy and histological observations indi-cated that traumatic shock was cause of his death. Moreover, histologically, we observed changes due to his congenital heart disease, such as right ventricular hypertrophy, heart failure cells in the lungs, sclerosis of the liver, and hyaline degeneration in the kidney. Furthermore, ischemic changes, shrinkage or loss of neurons, were seen in hippocampus, and swelling of astrocytes in both cortex and hippocampus were also observed. These observations lead us to speculate that a hypoxic episode may have caused his accidental death while driving.
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Journal Title |
The journal of medical investigation : JMI
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ISSN | 13431420
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NCID | AA11166929
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Volume | 46
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Issue | 1-2
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Start Page | 115
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End Page | 119
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Sort Key | 115
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Published Date | 1999
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Remark | |
FullText File | |
language |
eng
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