| ID | 117171 |
| Title Alternative | A case of myasthenia gravis induced by nivolumab
ニボルマブによる重症筋無力症
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| Author |
Morimoto, Masami
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Ishikawa, Masashi
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Tashiro, Yoshihiko
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Takechi, Hirokazu
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
KAKEN Search Researchers
Matsuyama, Kazuo
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Miyauchi, Takayuki
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Kitagawa, Tetsuya
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
|
| Keywords | nivolumab
immune-related adverse events
myasthenia gravis
|
| Content Type |
Journal Article
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| Description | A ７０s female suffering from recurrent gastric cancer presented with ptosis, dysphagia and lower limb and neck muscles weakness with elevation of serum CK levels after second treatment with the immune checkpoint inhibitor nivolumab. The symptoms suggested myasthenia gravis （MG）, although anti-acetylcholine receptor antibody and muscle-specific receptor tyrosine kinase antibody were negative. Steroid treatment quickly normalized CK levels and relieved MG symptoms. Nivolumab-induced MG can rapidly become severe and potentially fatal, and a prompt and accurate response is desirable.
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| Journal Title |
Shikoku Acta Medica
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| ISSN | 00373699
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| NCID | AN00102041
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| Publisher | 徳島医学会
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| Volume | 78
|
| Issue | 1-2
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| Start Page | 65
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| End Page | 70
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| Sort Key | 65
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| Published Date | 2022-04-25
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| FullText File | |
| language |
jpn
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| TextVersion |
Publisher
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| departments |
Medical Sciences
University Hospital
|
