薬疹

According to the dermatological literature in Japan, the drug eruptions in the aged (over 60 years old) are recently incresing. It is explained by the recent increase of population in the aged and of medication for them. Clinical manifestations of drug eruption occured in the aged are reported as photosensitivity (21.0%), lichenoid erption (15.5%), macropapular (13.6%), erythema mutiforme (8.1%), erythroderm a (5.2%), bullous eruptions (4.9%), fixed eruptions (4.9%), TEN (4.5%), urticaria (3.2%), and MCOS (1.9%). Photosensitivity and lichenoid erption are the two of the most common in the aged. The causative drugs of two forms include antibiotics (especially new quinolon), anti-hypertensive drugs and vasodilators, nonsteroidal inflammatory drugs, and anticancer drugs.