ID | 118711 |
Author |
Murata, Takashi
National Hospital Organization Kyoto Medical Center
Hosoda, Kiminori
National Cerebral and Cardiovascular Center
Nishimura, Kunihiro
National Cerebral and Cardiovascular Center
Miyamoto, Yoshihiro
National Cerebral and Cardiovascular Center
Sakane, Naoki
National Hospital Organization Kyoto Medical Center
Satoh-Asahara, Noriko
National Hospital Organization Kyoto Medical Center
Toyoda, Masao
Tokai University
Hirota, Yushi
Kobe University
Matsuhisa, Munehide
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Kuroda, Akio
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Kato, Ken
National Hospital Organization Osaka National Hospital
Kouyama, Ryuji
Tsuchiura Kyodo General Hospital
Miura, Junnosuke
Tokyo Women’s Medical University
Tone, Atsuhito
Okayama Saiseikai General Hospital
Kasahara, Masato
Nara Medical University
Kasama, Shu
Nara Medical University
Suzuki, Shota
Nara Medical University
Ito, Yukie
Nara Medical University
Watanabe, Tomokazu
National Hospital Organization Kyoto Medical Center
Suganuma, Akiko
National Hospital Organization Kyoto Medical Center
Shen, Zhuo
Tokyo Women’s Medical University
Kobayashi, Hiroko
Tokyo Women’s Medical University
Takagi, Satoshi
Tokyo Women’s Medical University
Hoshina, Sari
Tokyo Women’s Medical University
Shimura, Kanako
Tokyo Women’s Medical University
Tsuchida, Yukiko
Tokyo Women’s Medical University
Kimura, Moritsugu
Tokai University
Saito, Nobumichi
Tokai University
Shimada, Akira
Saitama Medical University
Oikawa, Yoichi
Saitama Medical University
Satomura, Atsushi
Saitama Medical University
Haisa, Akifumi
Saitama Medical University
Kawashima, Satoshi
Kanda Naika Clinic
Meguro, Shu
Keio University
Itoh, Hiroshi
Keio University
Saisho, Yoshifumi
Keio University
Irie, Junichiro
Keio University
Tanaka, Masami
Keio University
Mitsuishi, Masanori
Keio University
Nakajima, Yuya
Keio University
Inaishi, Jun
Keio University
Kinouchi, Kenichiro
Keio University
Yamaguchi, Shintaro
Keio University
Itoh, Arata
Keio University
Sugiyama, Kazutoshi
Keio University
Yagi, Kazuma
Keio University
Tsuchiya, Tami
Keio University
Kodani, Noriko
Keio University
Shimizu, Ikki
Sakakibara Heart Institute of Okayama
Fukuda, Tetsuya
Sakakibara Heart Institute of Okayama
Kusunoki, Yoshiki
Hyogo College of Medicine
Katsuno, Tomoyuki
Hyogo College of Medicine
Matoba, Yuka
National Hospital Organization Kokura Medical Center
Hitaka, Yumi
National Hospital Organization Kokura Medical Center
Abe, Kentaro
National Hospital Organization Kokura Medical Center
Tanaka, Natsuko
National Hospital Organization Kokura Medical Center
Taniguchi, Ryoko
National Hospital Organization Kokura Medical Center
Nagao, Toshihiko
National Hospital Organization Kokura Medical Center
Hida, Kazuyuki
National Hospital Organization Okayama Medical Center
Iseda, Izumi
National Hospital Organization Okayama Medical Center
Takeda, Masaya
National Hospital Organization Okayama Medical Center
Matsushita, Yuichi
National Hospital Organization Okayama Medical Center
Tenta, Masafumi
National Hospital Organization Okayama Medical Center
Tanaka, Tsuyoshi
National Hospital Organization Mie Chuo Medical Center
Kouyama, Kunichi
National Hospital Organization Hyogo-Chuo National Hospital
Fukunaga, Michiru
National Hospital Organization Hyogo-Chuo National Hospital
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Keywords | Time below range
Intermittent-scanning continuous glucose monitoring
Education
Randomized trial
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Content Type |
Journal Article
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Description | Aims: We conducted a randomized, crossover trial to compare intermittent-scanning continuous glucose monitoring (isCGM) device with structured education (Intervention) to self-monitoring of blood glucose (SMBG) (Control) in the reduction of time below range.
Methods: This crossover trial involved 104 adults with type 1 diabetes mellitus (T1DM) using multiple daily injections. Participants were randomly allocated to either sequence Intervention/Control or sequence Control/Intervention. During the Intervention period which lasted 84 days, participants used the first-generation FreeStyle Libre (Abbott Diabetes Care, Alameda, CA, USA) and received structured education on how to prevent hypoglycemia based on the trend arrow and by frequent sensor scanning (≥10 times a day). Confirmatory SMBG was conducted before dosing insulin. The Control period lasted 84 days. The primary endpoint was the decrease in the time below range (TBR; <70 mg/dL). Results: The time below range was significantly reduced in the Intervention arm compared to the Control arm (2.42 ± 1.68 h/day [10.1 %±7.0 %] vs 3.10 ± 2.28 h/day [12.9 %±9.5 %], P = 0.012). The ratio of high-risk participants with low blood glucose index >5 was significantly reduced (8.6 % vs 23.7 %, P < 0.001). Conclusions: The use of isCGM combined with structured education significantly reduced the time below range in patients with T1DM. |
Journal Title |
Diabetes Research and Clinical Practice
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ISSN | 01688227
18728227
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NCID | AA1152533X
AA1044374X
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Publisher | Elsevier
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Volume | 195
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Start Page | 110147
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Published Date | 2022-11-14
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Rights | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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DOI (Published Version) | |
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language |
eng
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Publisher
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departments |
Institute of Advanced Medical Sciences
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