| ID | 110829 |
| Author |
Miyamoto, Hidenori
Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
Kurita, Nobuhiro
Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
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Nishioka, Masanori
Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
Ando, Tsutomu
Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
Tashiro, Takashi
Department of Human Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
Hirokawa, Mitsuyoshi
Department of Human Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
Shimada, Mitsuo
Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
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|
| Keywords | neuroendocrine cell carcinoma
rectum
Ki-67
|
| Content Type |
Journal Article
|
| Description | A 56-year-old man was admitted to our hospital because of anal bleeding. Colonoscopy and barium enema revealed type 4 tumor in the rectum. Biopsy revealed poorly differentiated adenocarcinoma. Low anterior resection with total mesorectal excision and lymph node dissection was performed. In immunohistochemical staining, chromogranin A and synaptophysin were positive at major lesion, and CEA were focal positive. The resected tumor was diagnosed pathologically as neuroendocrine cell carcinoma. The Ki-67 labeling index (LI) was 87.8%, so proliferative activity and potential malignancy was very high. Multiple metastatic tumors appeared in pelvis and lung eight months after operation. Treatment for neuroendocrine cell carcinoma of the rectum was controversial. Surgical resection and adjuvant chemotherapy might be one of the methods for gastrointestinal neruroendocrine cell carcinoma.
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| Journal Title |
The journal of medical investigation : JMI
|
| ISSN | 13431420
|
| NCID | AA11166929
|
| Volume | 53
|
| Issue | 3-4
|
| Start Page | 317
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| End Page | 320
|
| Sort Key | 317
|
| Published Date | 2006-08
|
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
|
| TextVersion |
Publisher
|
| departments |
Medical Sciences
|
