ID | 114197 |
Title Alternative | TGs and CV Events
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Author |
Kajikawa, Masato
Hiroshima University
Maruhashi, Tatsuya
Hiroshima University
Kishimoto, Shinji
Hiroshima University
Matsui, Shogo
Hiroshima University
Hashimoto, Haruki
Hiroshima University
Takaeko, Yuji
Hiroshima University
Mohamad Yusoff, Farina
Hiroshima University
Kihara, Yasuki
Hiroshima University
Chayama, Kazuaki
Hiroshima University
Goto, Chikara
Hiroshima International University
Noma, Kensuke
Hiroshima University
Nakashima, Ayumu
Hiroshima University
Tomiyama, Hirofumi
Tokyo Medical University
Takase, Bonpei
National Defense Medical College Research Institute
Kohro, Takahide
Jichi Medical University
Suzuki, Toru
University of Leicester
Ishizu, Tomoko
University of Tsukuba
Ueda, Shinichiro
University of the Ryukyu
Yamazaki, Tsutomu
The University of Tokyo
Furumoto, Tomoo
Hokkaido University
Kario, Kazuomi
Jichi Medical University
Inoue, Teruo
Dokkyo Medical University
Koba, Shinji
Showa University
Watanabe, Kentaro
Yamagata University
Takemoto, Yasuhiko
Osaka City University
Hano, Takuzo
Wakayama Medical University
Sata, Masataka
The University of Tokushima
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Ishibashi, Yutaka
Shimane University
Node, Koichi
Saga University
Maemura, Koji
Nagasaki University
Ohya, Yusuke
University of the Ryukyus
Furukawa, Taiji
Teikyo University
Ito, Hiroshi
Okayama University
Ikeda, Hisao
Teikyo University
Yamashina, Akira
Tokyo Medical University
Higashi, Yukihito
Hiroshima University
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Keywords | Atherosclerosis
Cardiovascular events
Triglycerides
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Content Type |
Journal Article
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Description | Background: Circulating triglyceride (TG) levels are a current focus as a residual risk for cardiovascular (CV) events. We evaluated the relationship between circulating TG levels and future CV events in patients with coronary artery disease (CAD) who were treated with conventional therapy.
Methods and Results: We analyzed data for 652 patients who were enrolled in the FMD-J Study A. We investigated the associations between serum TG levels and first major CV events (death from CV cause, nonfatal acute coronary syndrome (ACS), nonfatal stroke, and CAD) for a 3-year follow-up period. Patients were divided into 4 groups based on serum TG level: low-normal (<100 mg/dL), high-normal (100–149 mg/dL), borderline hypertriglyceridemia (150–199 mg/dL), and moderate hypertriglyceridemia (≥200 mg/dL). During a median follow-up period of 46.6 months, 14 patients died (9 from CV causes), 16 had nonfatal ACS, 6 had nonfatal stroke, and 54 had CAD. The Kaplan-Meier curves for first major CV event among the 4 groups were significantly different (P=0.04). After adjustment for various confounders, serum TG level ≥100 mg/dL were significantly associated with an increased risk of first major CV events compared with serum TG level <100 mg/dL. Conclusions: Serum TG level may be a surrogate marker for predicting CV events in patients with CAD. |
Journal Title |
Circulation Journal
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ISSN | 13469843
13474820
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NCID | AA11591968
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Publisher | The Japanese Circulation Society
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Volume | 83
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Issue | 5
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Start Page | 1064
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End Page | 1071
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Published Date | 2019-04-25
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
Medical Sciences
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