| ID | 114858 |
| Title Alternative | Tolerability and efficacy of a chemotherapy regimen avoiding Anthracycline for HER 2 positive elderly and poor risked breast cancer patients
高齢者乳癌に対するAnthracycline回避レジメン
|
| Author |
Morimoto, Masami
Tokushima University
Tashiro, Yoshihiko
Shikoku Central Hospital
Matsuyama, Kazuo
Shikoku Central Hospital
Miyauchi, Takayuki
Shikoku Central Hospital
Ishikawa, Masashi
Shikoku Central Hospital
Aoyama, Mariko
Tokushima University
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Toba, Hiroaki
Tokushima University
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Tangoku, Akira
Tokushima University
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|
| Keywords | HER２ positive breast cancer
Elderly patients
Neo-adjuvant chemotherapy
RDI
pCR rate
|
| Content Type |
Journal Article
|
| Description | Tolerability and efficacy of chemotherapy avoiding anthracycline regimen were examined histologically in ER negative and HER２positive elderly and poor risked breast cancer patients because of serious toxicity of Anthracycline regimen. Neo-adjuvant chemotherapy with ４ to ６ courses of Paclitaxel with Trastuzumab was given to ６ patients, Pertuzumab was added in 2 cases to obtain complete response. Adverse events were controllable, the primary treatment was completed without reducing the dose of drugs（RDI was １００％）. Clinical CR rate was recognized in all ６ patients and pathological CR was proved in all of the operated５cases.
|
| Journal Title |
Shikoku Acta Medica
|
| ISSN | 00373699
|
| NCID | AN00102041
|
| Publisher | 徳島医学会
|
| Volume | 76
|
| Issue | 1-2
|
| Start Page | 69
|
| End Page | 72
|
| Sort Key | 69
|
| Published Date | 2020-04-25
|
| EDB ID | |
| FullText File | |
| language |
jpn
|
| TextVersion |
Publisher
|
| departments |
University Hospital
Medical Sciences
|
