| ID | 114702 |
| Author |
Nakamura, Shingen
Tokushima University
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Miki, Hirokazu
Tokushima University
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Iwasa, Masami
Tokushima University
Ikegame, Akishige
Tokushima University
Maruhashi, Tomoko
Tokushima prefecture Naruto hospital
Uemura, Munenori
Tokushima University
Takahashi, Mamiko
Tokushima University
Oda, Asuka
Tokushima University
Fujii, Shiro
Tokushima University
Tokushima University Educator and Researcher Directory
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Abe, Masahiro
Tokushima University
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|
| Keywords | adenosine deaminase
multiple myeloma
pleural effusion
|
| Content Type |
Journal Article
|
| Description | A 50-year-old man with immunoglobulin A type multiple myeloma (MM) was referred to our hospital after bortezomib therapy. He had high alkaline phosphatase and lactate dehydrogenase levels. Computed tomography showed osteolytic and osteoblastic bone lesions. Response to salvage chemotherapy was temporary, and he developed a right pleural effusion with high adenosine deaminase (ADA) levels. He died from bleeding associated with a pelvic bone fracture 9 months later. ADA mRNA expression and ADA secretion of the MM cells from the patient were higher than those from myeloma cell lines tested. Clinical relevance of high ADA expression in MM cells is warranted.
|
| Journal Title |
International Journal of Myeloma
|
| ISSN | 21873143
|
| NCID | AA12766965
|
| Publisher | Japanese Society of Myeloma
|
| Volume | 7
|
| Issue | 1
|
| Start Page | 1
|
| End Page | 5
|
| Published Date | 2017
|
| EDB ID | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
|
| TextVersion |
Publisher
|
| departments |
Medical Sciences
University Hospital
|
