ID | 109759 |
Title Transcription | シンフゼン オ ガッペイ シタ ジンケッカンセイ コウケツアツ ニ タイスル ケイヒテキ ジンドウミャク ケイセイジュツ ノ ユウコウセイ
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Title Alternative | Efficacy of percutaneous transluminal renal angioplasty for renovascular hypertension complicated with heart failure
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Author |
Imada, Kumiko
Junior resident, Tokushima University Hospital
Yagi, Shusuke
Division of Cardiology, Tokushima University Hospital
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Yamaguchi, Koji
Division of Cardiology, Tokushima University Hospital
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Wakatsuki, Tetsuzo
Division of Cardiology, Tokushima University Hospital
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Ise, Takayuki
Division of Cardiology, Tokushima University Hospital
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Ota, Rie
Division of Cardiology, Tokushima University Hospital
Kadota, Muneyuki
Division of Cardiology, Tokushima University Hospital
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Takashima, Akira
Division of Cardiology, Tokushima University Hospital
Matsuura, Tomomi
Division of Cardiology, Tokushima University Hospital
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Yamada, Hirotsugu
Division of Cardiology, Tokushima University Hospital
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Soegi, Takeshi
Division of Cardiology, Tokushima University Hospital
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Akaike, Masashi
Division of Cardiology, Tokushima University Hospital
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Sata, Masataka
Division of Cardiology, Tokushima University Hospital
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Keywords | heart failure
cardiac disturbance syndrome
percutaneous transluminal renal angioplasty
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Content Type |
Journal Article
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Description | 【Background】
Percutaneous transluminal renal angioplasty (PTRA) is recommended for patients with heart failure due to renovascular hypertension ; however, the clinical characteristics of the patients and the effects of PTRA on heart failure and cardiorenal function have not been elucidated. 【Methods】 We retrospectively analyzed data for 4 PTRA-treated patients (male/female, 1/3 ; mean age, 70.0±10 years ; mean left ventricular ejection fraction, 51.5±15.2%) with heart failure due to renovascular hypertension and evaluated the effects of PTRA on heart failure and cardiorenal function 6 months after treatment. 【Results】 All patients had pro-arteriosclerotic diseases including diabetes mellitus, essential thrombocythemia, heparin cofactor II deficency, metabolic syndrome, and familial hypercholesterolemia, and 3 patients had ischemic heart disease. No abdominal bruit was heard and mean plasma renin activity was 4.5±3.6 ng/ml/hr, which was not elevated, contrary to expectation. All contralateral kidneys of PTRA were nonfunctioning, suggesting bilateral kidneys were disturbed in all patients. In all patients, PTRA was successfully performed and resolved heart failure. PTRA resulted in decreases in systolic blood pressure from 157±18 to 124±8.6 mmHg, mean serum creatinine from 3.2±2.6 to 2.7±2.2 mg/dl, and mean BNP from 919±998 to 243±291 pg/ml at 6 months after treatment. PTRA did not change left ventricular ejection fraction, a parameter of systolic fraction evaluated by an echocardiogram ; however, PTRA improved E/e’, a parameter of left ventricular diastolic fraction, from 16.1±5.2 to 9.7±3.7. None of the patients were hospitalized due to heart failure during the 6-month period after PTRA. 【Conclusions】 Patients with heart failure with cardiovascular risk factors should be screened for renovascular hypertension regardless of abdominal bruit or plasma renin activity. PTRA is effective for resolving heart failure and for improving renal and cardiac diastolic functions in patients with renovascular hypertension complicated with heart failure. |
Journal Title |
四国医学雑誌
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ISSN | 00373699
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NCID | AN00102041
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Publisher | 徳島医学会
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Volume | 70
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Issue | 3-4
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Start Page | 87
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End Page | 92
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Sort Key | 87
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Published Date | 2014-08-25
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Remark | P.91著者英語表記 : Soegi(ソエギ)は、Soeki(ソエキ)が正しいと思われる。
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EDB ID | |
FullText File | |
language |
jpn
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TextVersion |
Publisher
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departments |
Medical Sciences
University Hospital
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