1. Tokushima University Departments
  2. Medical Sciences
  3. Nokihara, Hiroshi

Medical Sciences Nokihara, Hiroshi

Published Date (desc)
Potential of fluoropyrimidine to be an immunologically optimal partner of immune checkpoint inhibitors through inducing immunogenic cell death for thoracic malignancies
Author Kozai, Hiroyuki/ Ogino, Hirokazu/ Mitsuhashi, Atsushi/ Nguyen, Na Thi/ Tsukazaki, Yuki/ Yabuki, Yohei/ Ozaki, Ryohiko/ Yoneda, Hiroto/ Sato, Seidai/ Hanibuchi, Masaki/ Shinohara, Tsutomu/ Nokihara, Hiroshi/ Nishioka, Yasuhiko/
Content Type Thesis or Dissertation
Journal Title Thoracic Cancer
Volume 15
Issue 5
Published Date 2023-12-26
departments University Hospital Medical Sciences
Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells
Author Yoneda, Hiroto/ Mitsuhashi, Atsushi/ Yoshida, Aito/ Ogino, Hirokazu / Itakura, Satoshi/ Nguyen, Na Thi/ Nokihara, Hiroshi/ Sato, Seidai/ Shinohara, Tsutomu/ Hanibuchi, Masaki/ Abe, Shinji/ Kaneko, Mika K./ Kato, Yukinari/ Nishioka, Yasuhiko/
Content Type Thesis or Dissertation
Journal Title Cancer Science
Volume 115
Issue 2
Published Date 2023-12-26
departments University Hospital Medical Sciences Pharmaceutical Sciences
An increased relative eosinophil count as a predictive dynamic biomarker in non-small cell lung cancer patients treated with immune checkpoint inhibitors
Author Takeuchi, Eiji/ Ogino, Hirokazu/ Kondo, Kensuke/ Okano, Yoshio/ Ichihara, Seiya/ Kunishige, Michihiro/ Kadota, Naoki/ Machida, Hisanori/ Hatakeyama, Nobuo/ Naruse, Keishi/ Nokihara, Hiroshi/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Thoracic Cancer
Volume 15
Issue 3
Published Date 2023-12-12
departments Medical Sciences University Hospital
A multicenter, open-label, phase II trial of pemetrexed plus bevacizumab in elderly patients with previously untreated advanced or recurrent nonsquamous non-small cell lung cancer
Author Yabuki, Yohei/ Hanibuchi, Masaki/ Takeuchi, Eiji/ Haku, Takashi/ Kanematsu, Takanori/ Nishimura, Naoki/ Toyoda, Yuko/ Mitsuhashi, Atsushi/ Otsuka, Kenji/ Sato, Seidai/ Goto, Hisatsugu/ Yoneda, Hiroto/ Ogino, Hirokazu/ Nokihara, Hiroshi/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Thoracic Cancer
Volume 14
Issue 32
Published Date 2023-09-17
departments Medical Sciences University Hospital
Pretreatment eosinophil counts as a predictive biomarker in non-small cell lung cancer patients treated with immune checkpoint inhibitors
Author Takeuchi, Eiji/ Kondo, Kensuke/ Okano, Yoshio/ Ichihara, Seiya/ Kunishige, Michihiro/ Kadota, Naoki/ Machida, Hisanori/ Hatakeyama, Nobuo/ Naruse, Keishi/ Ogino, Hirokazu/ Nokihara, Hiroshi/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Thoracic Cancer
Volume 14
Issue 30
Published Date 2023-09-05
departments Medical Sciences University Hospital
A case of successful treatment with eltrombopag for severe immune-related thrombocytopenia induced by atezolizumab : Case report
Author Harada, Saki/ Imakura, Takeshi/ Sato, Seidai/ Nokihara, Hiroshi/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title The Journal of Medical Investigation
Volume 70
Issue 3-4
Published Date 2023-08
departments University Hospital Medical Sciences
Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade
Author Mitsuhashi, Atsushi/ Koyama, Kazuya/ Ogino, Hirokazu/ Afroj, Tania/ Nguyen, Na Thi/ Yoneda, Hiroto/ Otsuka, Kenji/ Sugimoto, Masamichi/ Kondoh, Osamu/ Nokihara, Hiroshi/ Hanibuchi, Masaki/ Takizawa, Hiromitsu/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Cell Reports
Volume 42
Issue 3
Published Date 2023-03-03
departments Medical Sciences University Hospital
Immune checkpoint inhibitor-related pneumonitis with atypical radiologic features in a patient with anti-aminoacyl-tRNA synthetase antibody
Author Ichihara, Seiya/ Ogino, Hirokazu/ Yoneda, Hiroto/ Haji, Keiko/ Kagawa, Kozo/ Murakami, Kojin/ Mima, Masato/ Aoi, Yu/ Mitsuhashi, Atsushi/ Tsukazaki, Yuki/ Yabuki, Yohei/ Ozaki, Ryohiko/ Sato, Seidai/ Nokihara, Hiroshi/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Respiratory Medicine Case Reports
Volume 41
Published Date 2022-12-15
departments Medical Sciences University Hospital
S-1 eliminates MDSCs and enhances the efficacy of PD-1 blockade via regulation of tumor-derived Bv8 and S100A8 in thoracic tumor
Author Nguyen, Na Thi/ Mitsuhashi, Atsushi/ Ogino, Hirokazu/ Kozai, Hiroyuki/ Yoneda, Hiroto/ Afroj, Tania/ Sato, Seidai/ Nokihara, Hiroshi/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type Thesis or Dissertation
Journal Title Cancer Science
Volume 114
Issue 2
Published Date 2022-10-26
departments Medical Sciences University Hospital
Efficacy and safety of second-line chemotherapy for patients with advanced non-small cell lung cancer complicated by interstitial lung disease
Author Otsuka, Kenji/ Nokihara, Hiroshi/ Mitsuhashi, Atsushi/ Ozaki, Ryohiko/ Yabuki, Yohei/ Yoneda, Hiroto/ Ogino, Hirokazu/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Thoracic Cancer
Volume 13
Issue 21
Published Date 2022-09-15
departments Medical Sciences University Hospital
Early mortality factors in immune checkpoint inhibitor monotherapy for advanced or metastatic non‑small cell lung cancer
Author Takeuchi, Eiji/ Kondo, Kensuke/ Okano, Yoshio/ Kunishige, Michihiro/ Kondo, Yoshihiro/ Kadota, Naoki/ Machida, Hisanori/ Hatakeyama, Nobuo/ Naruse, Keishi/ Ogino, Hirokazu/ Nokihara, Hiroshi/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Journal of Cancer Research and Clinical Oncology
Volume 149
Issue 7
Published Date 2022-07-24
departments Medical Sciences University Hospital
Efficacy of osimertinib in epidermal growth factor receptor-mutated non-small-cell lung cancer patients with pleural effusion
Author Nokihara, Hiroshi/ Ogino, Hirokazu/ Mitsuhashi, Atsushi/ Kondo, Kensuke/ Ogawa, Ei/ Ozaki, Ryohiko/ Yabuki, Yohei/ Yoneda, Hiroto/ Otsuka, Kenji/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title BMC Cancer
Volume 22
Published Date 2022-06-01
departments University Hospital Medical Sciences
Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis A Randomized Clinical Trial
Author Oki, Ryosuke/ Izumi, Yuishin/ Fujita, Koji/ Miyamoto, Ryosuke/ Nodera, Hiroyuki/ Sato, Yasutaka/ Sakaguchi, Satoshi/ Nokihara, Hiroshi/ Kanai, Kazuaki/ Tsunemi, Taiji/ Hattori, Nobutaka/ Hatanaka, Yuki/ Sonoo, Masahiro/ Atsuta, Naoki/ Sobue, Gen/ Shimizu, Toshio/ Shibuya, Kazumoto/ Ikeda, Ken/ Kano, Osamu/ Nishinaka, Kazuto/ Kojima, Yasuhiro/ Oda, Masaya/ Komai, Kiyonobu/ Kikuchi, Hitoshi/ Kohara, Nobuo/ Urushitani, Makoto/ Nakayama, Yoshiaki/ Ito, Hidefumi/ Nagai, Makiko/ Nishiyama, Kazutoshi/ Kuzume, Daisuke/ Shimohama, Shun/ Shimohata, Takayoshi/ Abe, Koji/ Ishihara, Tomohiko/ Onodera, Osamu/ Isose, Sagiri/ Araki, Nobuyuki/ Morita, Mitsuya/ Noda, Kazuyuki/ Toda, Tatsushi/ Maruyama, Hirofumi/ Furuya, Hirokazu/ Teramukai, Satoshi/ Kagimura, Tatsuo/ Noma, Kensuke/ Yanagawa, Hiroaki/ Kuwabara, Satoshi/ Kaji, Ryuji/
Content Type Thesis or Dissertation
Journal Title JAMA Neurology
Volume 79
Issue 6
Published Date 2022-05-09
departments University Hospital Medical Sciences
Radiation-associated Angiosarcoma Presenting as Massive Pleural Effusion
Author Ogino, Hirokazu/ Tobiume, Makoto/ Kagawa, Kozo/ Kawano, Hiroshi/ Sakaguchi, Satoshi/ Saijo, Atsuro/ Matsumoto, Daisuke/ Takizawa, Hiromitsu/ Morikawa, Yuriko/ Bando, Yoshimi/ Goto, Hisatsugu/ Nokihara, Hiroshi/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Internal Medicine
Volume 61
Issue 9
Published Date 2022-05-01
departments Medical Sciences University Hospital
Lenvatinib-induced Interstitial Pneumonia in a Patient with Hepatocellular Carcinoma
Author Imakura, Takeshi/ Sato, Seidai/ Tomonari, Tetsu/ Murakami, Kojin/ Takahashi, Naoki/ Naito, Nobuhito/ Mima, Masato/ Kagawa, Kozo/ Koyama, Kazuya/ Nishimura, Haruka/ Kawano, Hiroshi/ Nokihara, Hiroshi/ Azuma, Masahiko/ Takayama, Tetsuji/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Internal Medicine
Volume 61
Issue 8
Published Date 2022-04-15
departments University Hospital Medical Sciences
Prevention of Pemetrexed-Induced Rash Using Low-Dose Corticosteroids : A Phase II Study
Author Sakurada, Takumi/ Nokihara, Hiroshi/ Koga, Tadashi/ Zamami, Yoshito/ Goda, Mitsuhiro/ Yagi, Kenta/ Hamano, Hirofumi/ Aizawa, Fuka/ Ogino, Hirokazu/ Sato, Seidai/ Kirino, Yasushi/ Goto, Hisatsugu/ Nishioka, Yasuhiko/ Ishizawa, Keisuke/
Content Type Journal Article
Journal Title The Oncologist
Volume 27
Issue 7
Published Date 2022-03-24
departments University Hospital Medical Sciences
Trends in Investigator-Initiated Clinical Studies at a University Hospital after Enforcement of the 2018 Clinical Trials Act in Japan
Author Sato, Yasutaka/ Sakaguchi, Satoshi/ Takechi, Kenshi/ Chuma, Masayuki/ Yagi, Kenta/ Kane, Chikako/ Goda, Mitsuhiro/ Hamano, Hirofumi/ Aoe, Yuki/ Nokihara, Hiroshi/ Kubo, Yoshiaki/ Hashimoto, Ichiro/ Yanagawa, Hiroaki/
Content Type Journal Article
Journal Title Biological and Pharmaceutical Bulletin
Volume 45
Issue 3
Published Date 2022-03-01
departments University Hospital Medical Sciences
Radiation therapy induces an abscopal effect and upregulates programmed death-ligand 1 expression in a patient with non-small cell lung cancer
Author Morita, Yutaka/ Saijo, Atsuro/ Nokihara, Hiroshi/ Mitsuhashi, Atsushi/ Yoneda, Hiroto/ Otsuka, Kenji/ Ogino, Hirokazu/ Bando, Yoshimi/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Thoracic Cancer
Volume 13
Issue 7
Published Date 2022-01-22
departments Medical Sciences University Hospital
A case of pulmonary pleomorphic carcinoma with preexisting interstitial pneumonia successfully treated with pembrolizumab
Author Sako, Masahiro/ Nokihara, Hiroshi/ Kondo, Kensuke/ Mitsuhashi, Atsushi/ Ozaki, Ryohiko/ Yabuki, Yohei/ Abe, Akane/ Yoneda, Hiroto/ Ogino, Hirokazu/ Otsuka, Kenji/ Uehara, Hisanori/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title Thoracic Cancer
Volume 13
Issue 1
Published Date 2021-12-03
departments University Hospital Medical Sciences
Correlation between immune-related adverse events and therapeutic effects of nivolumab in patients with malignant pleural mesothelioma
Author Yoneda, Hiroto/ Nokihara, Hiroshi/ Mitsuhashi, Atsushi/ Ozaki, Ryohiko/ Yabuki, Yohei/ Ogino, Hirokazu/ Otsuka, Kenji/ Nishioka, Yasuhiko/
Content Type Journal Article
Journal Title BMC Pulmonary Medicine
Volume 21
Published Date 2021-11-15
departments University Hospital Medical Sciences
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