ID | 118350 |
Title Alternative | Pancreatectomy in patients with LC
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Author |
Teraoku, Hiroki
Tokushima University
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Morine, Yuji
Tokushima University
Tokushima University Educator and Researcher Directory
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Ikemoto, Tetsuya
Tokushima University
Tokushima University Educator and Researcher Directory
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Saito, Yu
Tokushima University
Tokushima University Educator and Researcher Directory
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Yamada, Shinichiro
Tokushima University
Tokushima University Educator and Researcher Directory
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Waki, Yuhei
Tokushima University
Okikawa, Shohei
Tokushima University
Miyazaki, Katsuki
Tokushima University
Nakasu, Chiharu
Tokushima University
Noma, Takayuki
Tokushima University
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Keywords | liver cirrhosis
pancreaticoduodenectomy
pancreatectomy
pancreas
surgery
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Content Type |
Journal Article
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Description | Background : Several reports have shown a high mortality rate in patients with liver cirrhosis (LC) who undergo pancreaticoduodenectomy, however, there are few reports on its long-term prognosis. Methods : Twelve patients with LC who had undergone pancreatic resection were enrolled. To compare clinicopathological variables, 159 non-LC patients who had undergone resection for pancreatic cancer were enrolled. Results : Pancreaticoduodenectomy (PD) was performed in 5 LC patients and distal pancreatectomy (DP) was performed in 7 LC patients. Patients in the LC group had more co-morbidities, lower platelet counts and higher Fib4 index than the non-LC group. The postoperative complication rate was higher in the LC group (83.3% vs 47.8%). While the postoperative hospital stay and 30-day mortality rate were not different, the 90-day mortality rate was higher in the LC group (25.0% vs 2.5% ; p < 0.01). Comparison by operative procedure showed no significant differences of postoperative outcomes in DP cases. However, in PD cases, postoperative complications were more frequent (100% vs 42.3%) and 90-day mortality was higher (40.0% vs 2.9% ; p < 0.01) in the LC group. Conclusions : PD resulted in higher postoperative morbidity and mortality rates in patients with LC compared with non-LC patients. DP could be tolerated in the LC patients.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA11166929
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Publisher | Tokushima University Faculty of Medicine
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Volume | 70
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Issue | 1-2
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Start Page | 189
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End Page | 194
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Sort Key | 189
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Published Date | 2023-02
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DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
University Hospital
Medical Sciences
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