| ID | 110284 |
| Title Transcription | ミギテユビ ニ キュウソクニ エソセイ ビョウヘン オ ショウジタ コウリンシシツ コウタイ ショウコウグン ノ 1レイ
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| Title Alternative | A case of antiphospholipid syndrome with rapidly progressive necrotic skin lesions on the right fingers
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| Author |
Niki, Mariko
The Post-graduate Education Center, Tokushima University Hospital
Tokushima University Educator and Researcher Directory
Inoue, Natsuko
Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Fukumoto, Daisuke
Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Yamamoto, Tadamasa
Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Ansai, Sinichi
Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Kubo, Yoshiaki
Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Tokushima University Educator and Researcher Directory
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Arase, Seiji
Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Tokushima University Educator and Researcher Directory
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| Keywords | rapidly progressive necrotic skin lesions
mixed connective tissue disease
lupus anticoagulant
antiphospholipid syndrome
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| Content Type |
Journal Article
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| Description | A ７７‐year‐old female was referred to our clinic in July ４，２００８ with a week history of rapidly progressive necrotic skin lesions on her right fingers. She had been under treatments of mixed connective tissue disease（MCTD）since １９９１. Laboratory findings revealed prolongation of activated partial thromboplastin time（aPTT）and the presence of lupus anticoagulant. We diagnosed this case as MCTD followed by antiphospholipid syndrome（APS）. After the treatment of Prostaglangin E１and Sarpogrelate hydrochloride, low dose of oral aspirin was started. Necrotic lesions of her fingers improved gradually, and she was discharged in September２１. APS should be considered when we see rapidly progressive necrotic skin lesions on patients with collagen deseases.
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| Journal Title |
四国医学雑誌
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| ISSN | 00373699
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| NCID | AN00102041
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| Publisher | 徳島医学会
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| Volume | 65
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| Issue | 3-4
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| Start Page | 98
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| End Page | 102
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| Sort Key | 98
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| Published Date | 2009-08-25
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| FullText File | |
| language |
jpn
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| TextVersion |
Publisher
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| departments |
Medical Sciences
University Hospital
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