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ID 118343
Title Alternative
PMR and RS3PE Syndrome
Author
Okura, Yoshihiro Tokushima University
Inaba, Kaori Tokushima University|Kaifu Tokushima Prefectural Hospital Tokushima University Educator and Researcher Directory
Inaba, Keisuke Tokushima University|Kaifu Tokushima Prefectural Hospital Tokushima University Educator and Researcher Directory
Takahashi, Ryosuke Kaifu Tokushima Prefectural Hospital
Keywords
PMR
RS3PE syndrome
c-reactive protein
prednisolone
Content Type
Journal Article
Description
Polymyalgia rheumatica (PMR) and remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome are common inflammatory rheumatic diseases in the elderly. In this study, we investigated the difference of the therapeutic responses between patients with PMR and RS3PE syndrome. Twenty-four patients with PMR and 12 patients with RS3PE syndrome were treated with initial dosages of 10-20 mg per day oral prednisolone, and the dosages were then tapered. Percentages of patients with negative c-reactive protein (CRP) after 8-week treatment were significantly more in RS3PE syndrome than in PMR. Percentages of patients with relapse during one-year treatment were less likely to be in RS3PE syndrome than in PMR. These differences observed between the two disorders were not associated with the level of initial CRP. There was no significant difference in percentages of patients with prednisolone-free remission after two-year treatment between PMR and RS3PE syndrome. These results indicate that the early response to the treatment is greater in RS3PE syndrome than in PMR.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
70
Issue
1-2
Start Page
145
End Page
149
Sort Key
145
Published Date
2023-02
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
University Hospital