ID | 115839 |
Author |
Onizuka, Yoko
Gunma University
Nagai, Kazue
Gunma University
Ideno, Yuki
Gunma University
Kitahara, Yoshikazu
Gunma University
Iwase, Akira
Gunma University
Yasui, Toshiyuki
Tokushima University
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Nakajima-Shimada, Junko
Gunma University
Hayashi, Kunihiko
Gunma University
|
Keywords | Follicle-stimulating hormone (FSH)
Estrone (E1)
Estradiol (E2)
Menopausal status
Measurement of sex hormones in urine
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Content Type |
Journal Article
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Description | Objective: We aimed to establish correlations for the levels of follicle-stimulating hormone (FSH), estrone (E1) and estradiol (E2) between urine and serum in premenopausal and postmenopausal women using immunoassays.
Methods: In this study of 92 women (61 postmenopausal, 31 premenopausal), both urine and blood specimens were collected on the same day and stored at 4 °C for analysis by chemiluminescent immunoassay, radioimmunoassay and/or electrochemiluminescent immunoassay. Results: There were correlations in the levels of FSH, E1 and E2 between urine and serum in both postmenopausal (r = 0.96 for FSH, r = 0.91 for E1, r = 0.80 for E2) and premenopausal (r = 0.98 for FSH, r = 0.92 for E1, r = 0.90 for E2) women. It is indicated that the correlations were stronger in the premenopausal group compared with the postmenopausal group, especially for FSH. Conclusion: The levels of FSH, E1 and E2 in urine correlated with those in the serum in premenopausal and postmenopausal women. Urine samples could be used instead of serum samples to measure hormone levels, which would reduce the difficulty of conducting large survey studies. |
Journal Title |
Clinical Biochemistry
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ISSN | 00099120
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NCID | AA00607603
AA11523221
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Publisher | The Canadian Society of Clinical Chemists|Elsevier
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Volume | 73
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Start Page | 105
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End Page | 108
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Published Date | 2019-08-20
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Rights | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
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language |
eng
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TextVersion |
Publisher
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departments |
Medical Sciences
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