| ID | 110201 |
| Title Transcription | ジヘイショウ ノ シンダン チリョウ サイゼンセン
|
| Title Alternative | Advances in neurology of autism
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| Author |
Mori, Kenji
Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School
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Fujii, Emiko
Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School
Miyazaki, Masahito
Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School
Kagami, Shoji
Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School
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|
| Keywords | autism
amygdale
mirror neuron system
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| Content Type |
Journal Article
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| Description | In this paper we review the pathophysiology of autism.1）The amygdala theory of autismThe network of neural regions that comprise the social brain includes the amygdala. There isa reduction in volume of amygdala in children with autism. The concentration of N-acetylaspartateis also decreased in amygdala of autistic brain. The amygdala is therefore proposed to be one ofseveral neural regions that are abnormal in autism.2）Mirror neuron dysfunction in autismChildren with autism underwent fMRI while imitating and observing emotional expressions.They showed no mirror neuron activity in the inferior frontal gyrus（pars opercularis）. Notably,activity in this area was inversely related to symptom severity in the social domain, suggestingthat a dysfunctional mirror neuron system may underlie the social deficits observed in autism.
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| Journal Title |
四国医学雑誌
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| ISSN | 00373699
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| NCID | AN00102041
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| Publisher | 徳島医学会
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| Volume | 63
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| Issue | 5-6
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| Start Page | 187
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| End Page | 193
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| Sort Key | 187
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| Published Date | 2007-12-20
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| FullText File | |
| language |
jpn
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| TextVersion |
Publisher
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| departments |
Medical Sciences
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