| ID | 101816 |
| Title Transcription | カブ チョクチョウ ガン ノ ジュツゼン ホウシャセン カガク リョウホウ ニヨル アタラシイ チリョウ センリャク
|
| Title Alternative | Preoperative chemoradiotherapy as a new strategy for lower advanced rectal cancer
|
| Author |
Ikemoto, Tetsuya
Department of Digestive and Pediatric Surgery
Tokushima University Educator and Researcher Directory
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Ando, Tsutomu
Department of Digestive and Pediatric Surgery
Nishioka, Masaki
Department of Digestive and Pediatric Surgery
Yawata, Yuko
Department of Surgery, Taoka Hospital
Terashima, Yoshiyasu
Department of Digestive and Pediatric Surgery
Ikushima, Hitoshi
Department of Radiology, Iustitute of Health Biosciences, The University of Tokushima Graduate School
Tokushima University Educator and Researcher Directory
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Tashiro, Seiki
Department of Surgery, Shikoku-Chuo Central Hospital
Tokushima University Educator and Researcher Directory
Shimada, Mitsuo
Department of Digestive and Pediatric Surgery
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|
| Keywords | preoperative chemoradiation
rectal cancer
5-Fluorouracil
|
| Content Type |
Journal Article
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| Description | Purpose : To report cases of advanced rectal cancer that showed significant responses after
administration of preoperative chemoradiation therapy. Methods : 5-Fluorouracil（5-FU, 300mg//day）was administered by 24-hour continuous intravenous infusion after cancers had been decreased in size by radiation（2Gy）administered for 20 days preoperatively. All patients then underwent low anterior resection with lymph node dissection（two cases had super-low anterior resection）. Results : Clinical stages of all patients were down-staged preoperatively. All of operations resulted in a curative resection of the cancer cells macroscopically. In one, histological examination revealed no residual cancer cells in the resected specimen（CR）. Conclusion : Preoperative chemoradiation therapy was demonstrated as a promising regimen for patients with advanced lower rectal cancer, and should be considered to extend indications for even laparoscopic operations for advanced rectal cancer; a therapy tailor made for advanced rectal cancer. |
| Journal Title |
四国医学雑誌
|
| ISSN | 00373699
|
| NCID | AN00102041
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| Publisher | 徳島医学会
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| Volume | 60
|
| Issue | 3-4
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| Start Page | 99
|
| End Page | 100
|
| Sort Key | 99
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| Published Date | 2004-08-25
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| Remark | |
| FullText File | |
| language |
jpn
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| departments |
University Hospital
Medical Sciences
|
