ID | 111488 |
Author |
Karabasil, Mileva R
The University of Tokushima|Belgrade University
Murdiastuti, Kwartarini
Gadjah Mada University
Purwanti, Nunuk
The University of Tokushima|Gadjah Mada University
Azlina, Ahmad
The University of Tokushima
Purevjav, Javkhlan
The University of Tokushima
Hasegawa, Takahiro
The University of Tokushima
Tokushima University Educator and Researcher Directory
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Yao, Chenjuan
The University of Tokushima
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Akamatsu, Tetsuya
The University of Tokushima
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Hosoi, Kazuo
The University of Tokushima
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|
Keywords | AQP5 mutant
trafficking
salivary gland
|
Content Type |
Journal Article
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Description | In the colony of Sprague-Dawley (SD) strain, we found that there were rats expressing a mutant AQP5, which has a point mutation at nt 308 (G308A), leading to a replacement of 103Gly with 103Asp in the 3rd transmembrane domain. The mutant molecule scarcely expressed in the acinar cells, probably because of ineffective trafficking. The mutant molecule, however, showed normal water permeability when assessed by the oocyte system.
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Journal Title |
The Journal of Medical Investigation
|
ISSN | 13496867
13431420
|
NCID | AA11166929
AA12022913
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Publisher | Faculty of Medicine Tokushima University
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Volume | 56
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Issue | Supplement
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Start Page | 398
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End Page | 400
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Sort Key | 398
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Published Date | 2009-12
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
|
departments |
Oral Sciences
Bioscience and Bioindustry
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