ID | 113342 |
Title Alternative | Radiotherapy for esophageal cancer
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Author |
Ikushima, Hitoshi
Tokushima University
Tokushima University Educator and Researcher Directory
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Kubo, Akiko
Tokushima University
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Kawanaka, Takashi
Tokushima University
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Kudo, Takaharu
Tokushima University
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Miyamoto, Hiroshi
Tokushima University
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Harada, Masafumi
Tokushima University
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Takayama, Tetsuji
Tokushima University
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Tangoku, Akira
Tokushima University
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Keywords | Clinical outcome
Chemoradiotherapy
Esophageal cancer
Radiotherapy
Neoadjuvant chemotherapy
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Content Type |
Journal Article
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Description | Purpose To assess the treatment results of definitive radiotherapy for esophageal cancer at Tokushima University Hospital and clarify the prognostic factors. Methods Seventy consecutive patients with esophageal cancer who underwent definitive radiotherapy between May 2004 and March 2012 were included in the present study. Local control rate, overall survival rate, and radiation morbidity were examined and univariate and multivariate analyses were performed to investigate prognostic factors. Results The 5-yearoverall survival rates of stages I, II, III, and IVA were 81%, 71%, 0%, and 9%, respectively. Performance status, clinical stage, and neoadjuvant chemotherapy were significant prognostic factors. A past history of interstitial pneumonia was associated with severe radiation-induced lung injury. Conclusions Patients who underwent definitive chemoradiotherapy for esophageal cancer in stage I/II showed good prognosis. However, treatment results of the patients in stage III/IV were not satisfactory, and those who could not undergo surgery after neoadjuvant chemotherapy had the worst prognosis.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA12022913
AA11166929
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Publisher | Tokushima University Faculty of Medicine
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Volume | 66
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Issue | 1-2
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Start Page | 99
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End Page | 105
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Sort Key | 99
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Published Date | 2019-02
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
University Hospital
Medical Sciences
Oral Sciences
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