大腸原発悪性リンパ腫の3例

Compared with carcinomas of the digestive organs, malignant lymphomas of the digestive organs are rare, especially those of the colon and rectum. Three patients with malignant lymphoma arising in the colon experienced at our hospital from １９９１ to ２０１０ are presented here. These ages ranged from ５９ to ７８. The male was two and the female was one. Two patients underwent ileocecal resection and one patient did extended right hemicolectomy, and two patients had partial resection of the ileum, because of tumor invaded. Histopathologically all three patients had non-Hodgkin’s lymphoma, B-cell type. According to LSG classification, all cases were of diffuse type, including two of large cell type, one of medium-sized cell type. As post operative adjuvant chemotherapy, CHOP and R-CHOP was given to two patients. IPI were H, HI, LI, respectively. As for prognosis, two patients died, and one patient is alive. Prognosis of malignant lymphoma of the colon is very poor, and combination of surgical operation and chemotherapy is very important for treatment.