ID | 118559 |
Author |
Kadoriku, Fumiya
Tokushima University
Fukuta, Kyotaro
Tokushima Prefectural Central Hospital
Atagi, Yuichiro
Ehime Prefectural Central Hospital
Shiozaki, Keito
Tokushima Prefectural Central Hospital
Daizumoto, Kei
Tokushima University
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Tomida, Ryotaro
Tokushima University
Ueno, Yoshiteru
Tokushima University
Kusuhara, Yoshito
Tokushima University
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Fukawa, Tomoya
Tokushima University
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Yanagihara, Yutaka
Ehime Prefectural Central Hospital
Yamaguchi, Kunihisa
Tokushima University
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Yamamoto, Yasuyo
Tokushima University
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Takahashi, Masayuki
Tokushima University
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Yamashi, Sadamu
Ehime Prefectural Central Hospital
Kan, Masaharu
Ehime Prefectural Central Hospital
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Keywords | Robot-assisted radical cystectomy
Intracorporeal ileal conduit
Older patients
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Content Type |
Journal Article
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Description | Background: Robot-assisted radical cystectomy (RARC) and intracorporeal urinary diversion are less invasive than conventional procedures. However, for older patients, cutaneous ureterostomy (CUS) may be preferred because urinary diversion using the intestine has a high incidence of perioperative complications and is highly invasive. The purpose of this study was to demonstrate the safety and efficacy of intracorporeal ileal conduit (ICIC) compared with CUS in patients aged 75 years or older who underwent RARC.
Methods: From October 2014 to December 2021, 82 patients aged 75 years or older who underwent RARC at Tokushima University Hospital, Tokushima Prefectural Central Hospital, or Ehime Prefectural Central Hospital were retrospectively reviewed. Of these, 52 and 25 patients who underwent ICIC and CUS, respectively, were included. After adjusting the patients’ characteristics using propensity score-matching, surgical results and prognoses were retrospectively compared. The propensity score was based on age, Eastern Cooperative Oncology Group Performance Status Scale (ECOG-PS), American Society of Anesthesiologists physical status classification (ASA-PS), clinical tumor stage, and neoadjuvant chemotherapy. Results: The median age was lower in the ICIC group compared with the CUS group, and the proportion of high-risk cases (ECOG-PS ≥ 2 or ASA-PS ≥ 3) did not differ. The median operation time was longer in the ICIC group, and estimated blood loss was higher, compared with the CUS group. There were no significant differences in the incidence of complications within the first 30 postoperative days, incidence of complications 30–90 days after surgery, 2 year overall survival, 2-year cancer-specific survival, and 2-year recurrence-free survival. The stent-free rate was significantly lower in the CUS group than that in the ICIC group. Conclusion: In older patients, the ICIC group showed non-inferior surgical and oncological outcomes compared with the CUS group. Urinary diversion following RARC in older patients should be carefully selected by considering not only the age but also the general condition (including comorbidities) of the patient. |
Journal Title |
BMC Urology
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ISSN | 14712490
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NCID | AA12035460
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Publisher | BioMed Central|Springer Nature
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Volume | 22
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Start Page | 174
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Published Date | 2022-11-07
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Rights | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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language |
eng
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departments |
University Hospital
Medical Sciences
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