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ID 118792
Title Alternative
Leptomeningeal carcinomatosis in SCCP
Author
Fukuta, Kyotaro Tokushima Prefectural Central Hospital
Shiozaki, Keito Tokushima Prefectural Central Hospital
Nakanishi, Ryoichi Tokushima Prefectural Central Hospital
Izaki, Hirofumi Tokushima Prefectural Central Hospital KAKEN Search Researchers
Kudo, Eiji Tokushima Prefectural Central Hospital
Keywords
brain metastasis
leptomeningeal carcinomatosis
prostate carcinoma
small cell carcinoma of the prostate
Content Type
Journal Article
Description
Introduction: Leptomeningeal carcinomatosis in small cell carcinoma of the prostate is rare.
Case presentation: A 69-year-old man visited our hospital due to dysuria and edema. Bilateral hydronephrosis and lymph node metastases due to a pelvic tumor were observed. Although the prostate-specific antigen level was normal, the tumor was suspected to originate from the prostate. He underwent percutaneous nephrostomy and prostate biopsy. Histopathology revealed small cell carcinoma accompanied by increased pro-gastrin-releasing peptide and neuron-specific enolase levels. After receiving systemic chemotherapy with carboplatin and etoposide and radiation therapy for prostate, these lesions gradually decreased in size, and tumor markers normalized. Ten months after the initial diagnosis, he developed consciousness disorder and seizure. Magnetic resonance imaging revealed leptomeningeal carcinomatosis without any other recurrences and elevated tumor markers. He died 4 weeks after these symptoms appeared.
Conclusion: Careful monitoring of the central nervous system should be considered in small cell carcinoma of the prostate patients.
Journal Title
IJU Case Reports
ISSN
2577171X
Publisher
Japanese Cancer Association|John Wiley & Sons
Volume
5
Issue
6
Start Page
493
End Page
496
Published Date
2022-08-11
Rights
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
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language
eng
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departments
University Hospital
Medical Sciences