ID | 118792 |
Title Alternative | Leptomeningeal carcinomatosis in SCCP
|
Author |
Fukuta, Kyotaro
Tokushima Prefectural Central Hospital
Shiozaki, Keito
Tokushima Prefectural Central Hospital
Nakanishi, Ryoichi
Tokushima Prefectural Central Hospital
Kudo, Eiji
Tokushima Prefectural Central Hospital
Fukawa, Tomoya
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Yamaguchi, Kunihisa
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Yamamoto, Yasuyo
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
|
Keywords | brain metastasis
leptomeningeal carcinomatosis
prostate carcinoma
small cell carcinoma of the prostate
|
Content Type |
Journal Article
|
Description | Introduction: Leptomeningeal carcinomatosis in small cell carcinoma of the prostate is rare.
Case presentation: A 69-year-old man visited our hospital due to dysuria and edema. Bilateral hydronephrosis and lymph node metastases due to a pelvic tumor were observed. Although the prostate-specific antigen level was normal, the tumor was suspected to originate from the prostate. He underwent percutaneous nephrostomy and prostate biopsy. Histopathology revealed small cell carcinoma accompanied by increased pro-gastrin-releasing peptide and neuron-specific enolase levels. After receiving systemic chemotherapy with carboplatin and etoposide and radiation therapy for prostate, these lesions gradually decreased in size, and tumor markers normalized. Ten months after the initial diagnosis, he developed consciousness disorder and seizure. Magnetic resonance imaging revealed leptomeningeal carcinomatosis without any other recurrences and elevated tumor markers. He died 4 weeks after these symptoms appeared. Conclusion: Careful monitoring of the central nervous system should be considered in small cell carcinoma of the prostate patients. |
Journal Title |
IJU Case Reports
|
ISSN | 2577171X
|
Publisher | Japanese Cancer Association|John Wiley & Sons
|
Volume | 5
|
Issue | 6
|
Start Page | 493
|
End Page | 496
|
Published Date | 2022-08-11
|
Rights | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
|
EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
|
TextVersion |
Publisher
|
departments |
University Hospital
Medical Sciences
|