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ID 117762
Title Alternative
Regression of LV hypertrophy by tafamidis
Author
Yamazaki, Hiromu Tokushima University
Tserensonom, Munkhtsetseg Tokushima University
Keywords
cardiomyopathy
hereditary amyloidosis
hypertrophic hepertrophy
Content Type
Journal Article
Description
Transthyretin amyloidosis (ATTR) variant is a life-threatening hereditary disease predominantly affecting the peripheral nervous system and heart. Tafamidis, which prevents the deposition of amyloid by stabilizing transthyretin, is available for the treatment of neuropathy and cardiomyopathy of ATTR. However, whether tafamidis could eliminate established amyloid deposits and improve cardiac function remains unknown. We reported a case of regression of left ventricular hypertrophy after tafamidis therapy in a patient with an ATTR variant.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
69
Issue
3-4
Start Page
320
End Page
322
Sort Key
320
Published Date
2022-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
University Hospital