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A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis

Author	Imakura, Takeshi/ Sato, Seidai/ Koyama, Kazuya/ Ogawa, Hirohisa/ Niimura, Takahiro/ Murakami, Kojin/ Yamashita, Yuya/ Haji, Keiko/ Naito, Nobuhito/ Kagawa, Kozo/ Kawano, Hiroshi/ Zamami, Yoshito/ Ishizawa, Keisuke/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	Respiratory Research
Volume	24
Published Date	2023-06-02
departments	University Hospital Medical Sciences

Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade

Author	Mitsuhashi, Atsushi/ Koyama, Kazuya/ Ogino, Hirokazu/ Afroj, Tania/ Nguyen, Na Thi/ Yoneda, Hiroto/ Otsuka, Kenji/ Sugimoto, Masamichi/ Kondoh, Osamu/ Nokihara, Hiroshi/ Hanibuchi, Masaki/ Takizawa, Hiromitsu/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type	Journal Article
Journal Title	Cell Reports
Volume	42
Issue	3
Published Date	2023-03-03
departments	Medical Sciences University Hospital

The lymphocyte-specific protein tyrosine kinase-specific inhibitor A-770041 attenuates lung fibrosis via the suppression of TGF-β production in regulatory T-cells

Author	Kagawa, Kozo/ Sato, Seidai/ Koyama, Kazuya/ Imakura, Takeshi/ Murakami, Kojin/ Yamashita, Yuya/ Naito, Nobuhito/ Ogawa, Hirohisa/ Kawano, Hiroshi/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	PLOS ONE
Volume	17
Issue	10
Published Date	2022-10-27
departments	Medical Sciences University Hospital

Lysophosphatidic acid, ceramide 1-phosphate and sphingosine 1-phosphate in peripheral blood of patients with idiopathic pulmonary fibrosis

Author	Tanaka, Tamotsu/ Koyama, Kazuya/ Takahashi, Naoko/ Morito, Katsuya/ Ali, Hanif/ Azuma, Momoyo/ Kagawa, Kozo/ Kawano, Hiroshi/ Hasi, Rumana Yesmin/ Aihara, Mutsumi/ Nishioka, Yasuhiko/
Content Type	Journal Article
Journal Title	The Journal of Medical Investigation
Volume	69
Issue	3-4
Published Date	2022-08
departments	Pharmaceutical Sciences University Hospital Medical Sciences Bioscience and Bioindustry

Lenvatinib-induced Interstitial Pneumonia in a Patient with Hepatocellular Carcinoma

Author	Imakura, Takeshi/ Sato, Seidai/ Tomonari, Tetsu/ Murakami, Kojin/ Takahashi, Naoki/ Naito, Nobuhito/ Mima, Masato/ Kagawa, Kozo/ Koyama, Kazuya/ Nishimura, Haruka/ Kawano, Hiroshi/ Nokihara, Hiroshi/ Azuma, Masahiko/ Takayama, Tetsuji/ Nishioka, Yasuhiko/
Content Type	Journal Article
Journal Title	Internal Medicine
Volume	61
Issue	8
Published Date	2022-04-15
departments	University Hospital Medical Sciences

Programmed death (PD)-1/PD-ligand 1 blockade mediates antiangiogenic effects by tumor-derived CXCL10/11 as a potential predictive biomarker

Author	Mitsuhashi, Atsushi/ Kondoh, Kensuke/ Horikawa, Kazuki/ Koyama, Kazuya/ Nguyen, Na Thi/ Afroj, Tania/ Yoneda, Hiroto/ Otsuka, Kenji/ Ogino, Hirokazu/ Nokihara, Hiroshi/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type	Journal Article
Journal Title	Cancer Science
Volume	112
Issue	12
Published Date	2021-10-10
departments	Medical Sciences University Hospital

Immunohistochemical Detection of Propionibacterium acnes in Granulomas for Differentiating Sarcoidosis from Other Granulomatous Diseases Utilizing an Automated System with a Commercially Available PAB Antibody

Author	Isshiki, Takuma/ Homma, Sakae/ Eishi, Yoshinobu/ Yabe, Matsuko/ Koyama, Kazuya/ Nishioka, Yasuhiko/ Yamaguchi, Tetsuo/ Uchida, Keisuke/ Yamamoto, Kurara/ Ohashi, Kenichi/ Arakawa, Atsushi/ Shibuya, Kazutoshi/ Sakamoto, Susumu/ Kishi, Kazuma/
Content Type	Journal Article
Journal Title	Microorganisms
Volume	9
Issue	8
Published Date	2021-08-04
departments	University Hospital Medical Sciences

Blockade of PD-1/PD-L1 Pathway Enhances the Antigen-Presenting Capacity of Fibrocytes

Author	Afroj, Tania/ Mitsuhashi, Atsushi/ Ogino, Hirokazu/ Saijo, Atsuro/ Otsuka, Kenji/ Yoneda, Hiroto/ Tobiume, Makoto/ Nguyen, Na Thi/ Goto, Hisatsugu/ Koyama, Kazuya/ Sugimoto, Masamichi/ Kondoh, Osamu/ Nokihara, Hiroshi/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	The Journal of Immunology
Volume	206
Issue	6
Published Date	2021-01-27
departments	Medical Sciences University Hospital

Development of improved method to identify and analyze lung fibrocytes with flow cytometry in a reporter mouse strain

Author	Kawano, Hiroshi/ Koyama, Kazuya/ Nishimura, Haruka/ Toyoda, Yuko/ Kagawa, Kozo/ Sato, Seidai/ Naito, Nobuhito/ Goto, Hisatsugu/ Inagaki, Yutaka/ Nishioka, Yasuhiko/
Content Type	Journal Article
Journal Title	Immunity, Inflammation and Disease
Volume	9
Issue	1
Published Date	2020-12-24
departments	University Hospital Medical Sciences

Lysophosphatidic Acid Regulates the Differentiation of Th2 Cells and Its Antagonist Suppresses Allergic Airway Inflammation

Author	Kondo, Mayo/ Tezuka, Toshifumi/ Ogawa, Hirohisa/ Koyama, Kazuya/ Bando, Hiroki/ Azuma, Masahiko/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	International Archives of Allergy and Immunology
Volume	182
Issue	1
Published Date	2020-08-26
departments	Medical Sciences University Hospital

Distinct improvement of pulmonary function, ground-glass opacity, hypoxia and physical findings in an idiopathic pulmonary fibrosis patient after pirfenidone treatment : a case report with a review of the literature

Author	Imakura, Takeshi/ Toyoda, Yuko/ Sato, Seidai/ Koyama, Kazuya/ Nishimura, Haruka/ Kagawa, Kozo/ Takahashi, Naoki/ Naito, Nobuhito/ Murakami, Kojin/ Kawano, Hiroshi/ Azuma, Masahiko/ Shinohara, Tsutomu/ Nishioka, Yasuhiko/
Content Type	Journal Article
Journal Title	The Journal of Medical Investigation
Volume	67
Issue	3-4
Published Date	2020-08
departments	University Hospital Medical Sciences

Anti-PD-1 antibody combined with chemotherapy suppresses the growth of mesothelioma by reducing myeloid-derived suppressor cells

Author	Otsuka, Kenji/ Mitsuhashi, Atsushi/ Goto, Hisatsugu/ Hanibuchi, Masaki/ Koyama, Kazuya/ Ogawa, Hirohisa/ Ogino, Hirokazu/ Saijo, Atsuro/ Kozai, Hiroyuki/ Yoneda, Hiroto/ Tobiume, Makoto/ Kishuku, Masatoshi/ Ishizawa, Keisuke/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	Lung Cancer
Volume	146
Published Date	2020-05-21
departments	Medical Sciences University Hospital

Blockade of Pan-Fibroblast Growth Factor Receptors Mediates Bidirectional Effects in Lung Fibrosis

Author	Morizumi, Shun/ Sato, Seidai/ Koyama, Kazuya/ Okazaki, Hiroyasu/ Chen, Yajuan/ Goto, Hisatsugu/ Kagawa, Kozo/ Ogawa, Hirohisa/ Nishimura, Haruka/ Kawano, Hiroshi/ Toyoda, Yuko/ Uehara, Hisanori/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	American Journal of Respiratory Cell and Molecular Biology
Volume	63
Issue	3
Published Date	2020-04-27
departments	Medical Sciences University Hospital

Functional analysis of human fibrocytes derived from monocytes reveals their profibrotic phenotype through paracrine effects

Author	Abe, Shuichi/ Sato, Seidai/ Aono, Yoshinori/ Azuma, Momoyo/ Kishi, Masami/ Koyama, Kazuya/ Takahashi, Naoki/ Kagawa, Kozo/ Kawano, Hiroshi/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	The Journal of Medical Investigation
Volume	67
Issue	1-2
Published Date	2020-02
departments	University Hospital Medical Sciences

The novel inhibitor PRI-724 for Wnt/β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice

Author	Okazaki, Hiroyasu/ Sato, Seidai/ Koyama, Kazuya/ Morizumi, Shun/ Abe, Shuichi/ Azuma, Momoyo/ Chen, Yajuan/ Goto, Hisatsugu/ Aono, Yoshinori/ Ogawa, Hirohisa/ Kagawa, Kozo/ Nishimura, Haruka/ Kawano, Hiroshi/ Toyoda, Yuko/ Uehara, Hisanori/ Kouji, Hiroyuki/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	Experimental Lung Research
Volume	45
Issue	7
Published Date	2019-07-12
departments	University Hospital Medical Sciences

Blockade of platelet-derived growth factor receptor-β, not receptor-α ameliorates bleomycin-induced pulmonary fibrosis in mice

Author	Kishi, Masami/ Aono, Yoshinori/ Satou, Seidai/ Koyama, Kazuya/ Azuma, Momoyo/ Abe, Shuichi/ Kawano, Hiroshi/ Kishi, Jun/ Toyoda, Yuko/ Okazaki, Hiroyasu/ Ogawa, Hirohisa/ Uehara, Hisanori/ Nishioka, Yasuhiko/
Content Type	Thesis or Dissertation
Journal Title	PLOS ONE
Volume	13
Issue	12
Published Date	2018-12-31
departments	University Hospital Medical Sciences

Anti-fibrotic efficacy of nintedanib in pulmonary fibrosis via the inhibition of fibrocyte activity

Author	Sato, Seidai/ Shinohara, Shintaro/ Hayashi, Shinya/ Morizumi, Shun/ Abe, Shuichi/ Okazaki, Hiroyasu/ Chen, Yanjuan/ Goto, Hisatsugu/ Aono, Yoshinori/ Ogawa, Hirohisa/ Koyama, Kazuya/ Nishimura, Haruka/ Kawano, Hiroshi/ Toyoda, Yuko/ Uehara, Hisanori/ Nishioka, Yasuhiko/
Content Type	Journal Article
Journal Title	Respiratory Research
Volume	18
Published Date	2017-09-15
departments	University Hospital Medical Sciences