ID | 113626 |
Title Alternative | 限局性前立腺癌に対するI-125 シード線源永久挿入による排尿障害予測因子
Predictive Factors for Prolonged Urination Disorder After Brachytherapy
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Author |
Daizumoto, Kei
The University of Tokushima
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Kusuhara, Yoshito
The University of Tokushima
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Fukawa, Tomoya
The University of Tokushima
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Yamamoto, Yasuyo
The University of Tokushima
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Yamaguchi, Kunihisa
The University of Tokushima
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Takahashi, Masayuki
The University of Tokushima
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Kubo, Akiko
The University of Tokushima
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Kawanaka, Takashi
The University of Tokushima
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Ikushima, Hitoshi
The University of Tokushima
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Kanayama, Hiro-omi
The University of Tokushima
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Keywords | Brachytherapy
Prostate cancer
International Prostate Symptom Score : IPSS
Lower Urinary Tract Symptom : LUTS
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Content Type |
Thesis or Dissertation
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Description | Background: We assessed the change in LUTS after prostate brachytherapy to reveal factors for prolonged urination disorder. Materials and Methods: Four hundred and fourpatients received prostate brachytherapy at our institution and were followed-up for at least 2 years. We evaluated the correlation of mean IPSS changes and clinical factors. Using multivariate analysis, we also evaluated clinical factors with potential to delay IPSS resolution. Results: In cases with prostate volume more than 30 cm3, radiation dose to 90% of prostate volume (D90) more than 160 Gy, and radiation dose to 30% of the urethral volume (UD30) more than 240 Gy, mean IPSS levels were significantly higher, even 30 months after treatment. On multivariate analysis, baseline IPSS more than 8 points and D90 more than 160 Gy were significant predictors for delayed IPSS resolution. Conclusion: Our data suggest that higher baseline IPSS and higher D90 were predictors for prolonged urination disorder.
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Journal Title |
in vivo
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ISSN | 0258851X
17917549
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NCID | AA10714348
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Publisher | International Institute of Anticancer Research
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Volume | 31
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Issue | 4
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Start Page | 755
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End Page | 761
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Published Date | 2017-07
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Remark | 内容要旨・審査要旨・論文本文の公開
本論文は,著者HIDEHISA MORIの学位論文として提出され,学位審査・授与の対象となっている。 P.755著者の英語表記に誤植(誤)YOSHIHITO KUSUHARA(正)YOSHITO KUSUHARA |
Rights | Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
ETD
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MEXT report number | 甲第3315号
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Diploma Number | 甲医第1419号
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Granted Date | 2019-05-23
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Degree Name |
Doctor of Medical Science
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Grantor |
Tokushima University
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departments |
University Hospital
Medical Sciences
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