| ID | 109899 |
| Title Transcription | トクシマ ダイガク ビョウイン ノウソッチュウ センター デノ ナイケイドウミャク キュウセイ ヘイソク ニ タイスル チリョウ センリャク
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| Title Alternative | Treatment strategy for acute ischemic stroke with internal carotid artery occlusion in the stroke care unit of Tokushima University Hospital
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| Author |
Inoko, Miki
The Post-graduate Education Center, Tokushima University Hospital|Department of Stroke Care Unit, Tokushima University Hospital
kuwayama, Kazuyuki
Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Nishi, Kyoko
The Post-graduate Education Center, Tokushima University Hospital|Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
KAKEN Search Researchers
Yamaguchi, Tadashi
Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Satomi, Jyunichiro
Department of Stroke Care Unit, Tokushima University Hospital|Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
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Yamamoto, Nobuaki
Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School
Tokushima University Educator and Researcher Directory
Kaji, Ryuji
Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School
Tokushima University Educator and Researcher Directory
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Nagahiro, Shinji
Department of Stroke Care Unit, Tokushima University Hospital|Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Tokushima University Educator and Researcher Directory
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|
| Keywords | ICA occlusion
intra-arterial endovascular therapy
recombinant tissue-type plasminogen activator （rt-PA）
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| Content Type |
Journal Article
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| Description | Objective : Strokes related to acute internal carotid artery （ICA） occlusion are associated with extremely poor prognosis. Recently, some studies have reported that the prognosis has been getting better by treating with intra-arterial endovascular therapy. We sought to evaluate clinical outcomes in patients with acute ischemic stroke attributable to ICA occlusion treated with intraarterial endovascular therapy or otherwise.
Methods : We reviewed ４４ patients who underwent treatment with intra-arterial endovascular therapy or otherwise in our stroke care unit （SCU） from January, ２０１１ to May, ２０１４. We compared the prognosis of patients in the ２ treatment groups （endovascular group, n＝２３ vs nonendovascular group, n＝２１）. Results : The rate of good prognosis （modified Rankin Score of ≦２） was significantly higher in the endovascular group than non-endovascular group （１７．４％ vs０％，p＝０．０４５）. The rate of patients who had extreme improvements of National Institutes of Health Stroke Scale （NIHSS） ≧８ was higher in the endovascular group than non-endovascular group （３０．４％ vs１４．３％）. Concerning the improvement of NIHSS ≧８, recombinant tissue-type plasminogen activator （rt-PA） or the left side ICA occlusion were associated significantly （p＝０．０１９, p＝０．０４２, respectively）. Although the hypothesis that endovascular therapy could contribute to extreme improvements of NIHSS wasn’t proved （p＝０．２０２）, there was one case that NIHSS was dramatically improved from ２２ to ０ by endovascular therapy. Conclusions : Intra-arterial endovascular therapy of ICA occlusion might result in improved clinical outcomes for indicated cases. |
| Journal Title |
四国医学雑誌
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| ISSN | 00373699
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| NCID | AN00102041
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| Publisher | 徳島医学会
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| Volume | 70
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| Issue | 5-6
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| Start Page | 167
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| End Page | 172
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| Sort Key | 167
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| Published Date | 2014-12-25
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| EDB ID | |
| FullText File | |
| language |
jpn
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| TextVersion |
Publisher
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| departments |
University Hospital
Medical Sciences
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