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ID 118036
Author
Umezaki, Yojiro Fukuoka Dental College
Watanabe, Motoko Tokyo Medical and Dental University
Shinohara, Yukiko Tokyo Medical and Dental University
Sugawara, Shiori Tokyo Medical and Dental University
Kawasaki, Kaoru Tokyo Medical and Dental University
Tu, Trang TH Tokyo Medical and Dental University
Suga, Takayuki Tokyo Medical and Dental University
Miura, Anna Tokyo Medical and Dental University
Takenoshita, Miho Tokyo Medical and Dental University
Sato, Yusuke Tokyo Medical and Dental University
Minami, Ichiro Tokyo Medical and Dental University
Oyama, Jun Tokyo Medical and Dental University
Toriihara, Akira Tokyo Medical and Dental University
Yoshikawa, Tatsuya Tokyo Medical and Dental University
Naito, Toru Fukuoka Dental College
Motomura, Haruhiko Tokyo Medical and Dental University
Toyofuku, Akira Tokyo Medical and Dental University
Keywords
phantom bite syndrome
cerebral blood flow
single-photon emission computed tomography
Content Type
Journal Article
Description
Background: Phantom bite syndrome (PBS) is characterized by an uncomfortable sensation during occlusion without any evident abnormality. A recent case–control study with single-photon emission computed tomography (SPECT) using 99mTc-ethyl cysteinate dimer could not find the specific features of regional cerebral blood flow (rCBF), which might be due to the heterogeneity of PBS. We analyzed the brain images of PBS corresponding to the clinical features by studying PBS subgroups.
Methods: This study contributes to elucidating the pathophysiology of PBS by evaluating regional brain perfusion on SPECT and its clinical features. We performed SPECT using 99mTc-ethyl cysteinate dimer in 44 patients with PBS. The SPECT images were analyzed qualitatively and quantitatively.
Results: Asymmetrical rCBF patterns were detected, corresponding to symptom laterality. Patients with PBS with right-side symptoms showed right-side-predominant rCBF asymmetry in the parietal region and left-side-predominant rCBF asymmetry in the thalamus, and vice versa. Moreover, the analysis of the association between rCBF and patient behaviors revealed that patients who blamed their dentists for their symptoms tended to have a symmetrical rCBF pattern.
Conclusion: Patients with PBS showed blood flow imbalance in the thalamus and parietal region corresponding to symptom laterality. There are two types of symmetrical and asymmetrical rCBF patterns in the pathophysiology of PBS despite similar clinical manifestations.
Journal Title
Neuropsychiatric Disease and Treatment
ISSN
11782021
Publisher
Dove Medical Press
Volume
16
Start Page
2277
End Page
2284
Published Date
2020-10-06
Rights
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
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language
eng
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departments
Medical Sciences