ID | 117191 |
Author |
Koga, Kayoko
Saga University|Fukuoka University
Hara, Megumi
Saga University
Shimanoe, Chisato
Saga University
Nishida, Yuichiro
Saga University
Furukawa, Takuma
Saga University
Iwasaka, Chiharu
Saga University
Tanaka, Keitaro
Saga University
Otonari, Jun
Kyushu University|International University of Health and Welfare
Ikezaki, Hiroaki
Kyushu University
Kubo, Yoko
Nagoya University
Kato, Yasufumi
Nagoya University
Tamura, Takashi
Nagoya University
Hishida, Asahi
Nagoya University
Matsuo, Keitaro
Aichi Cancer Center Research Institute|Nagoya University
Ito, Hidemi
Aichi Cancer Center Research Institute|Nagoya University
Nakamura, Yohko
Chiba Cancer Center Research Institute
Kusakabe, Miho
Chiba Cancer Center Research Institute
Nishimoto, Daisaku
Kagoshima University
Shibuya, Keiichi
Kagoshima University
Suzuki, Sadao
Nagoya City University
Watanabe, Miki
Nagoya City University
Ozaki, Etsuko
Kyoto Prefectural University of Medicine
Matsui, Daisuke
Kyoto Prefectural University of Medicine
Kuriki, Kiyonori
University of Shizuoka
Takashima, Naoyuki
Kindai University|Shiga University of Medical Science
Kadota, Aya
Shiga University of Medical Science
Arisawa, Kokichi
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Katsuura‑Kamano, Sakurako
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Takeuchi, Kenji
Nagoya University
Wakai, Kenji
Nagoya University
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Content Type |
Journal Article
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Description | Elucidating the risk factors for chronic kidney disease is important for preventing end-stage renal disease and reducing mortality. However, little is known about the roles of psychosocial stress and stress coping behaviors in deterioration of the renal function, as measured by the estimated glomerular filtration rate (eGFR). This cross-sectional study of middle-aged and older Japanese men (n = 31,703) and women (n = 38,939) investigated whether perceived stress and coping strategies (emotional expression, emotional support seeking, positive reappraisal, problem solving, and disengagement) were related to the eGFR, with mutual interactions. In multiple linear regression analyses adjusted for age, area, lifestyle factors, and psychosocial variables, we found a significant inverse association between perceived stress and the eGFR in men (Ptrend = 0.02), but not women. This male-specific inverse association was slightly attenuated after adjustment for the history of hypertension and diabetes and was more evident in lower levels of emotional expression (Pinteraction = 0.003). Unexpectedly, problem solving in men (Ptrend < 0.001) and positive reappraisal in women (Ptrend = 0.002) also showed an inverse association with the eGFR. Perceived stress may affect the eGFR, partly through the development of hypertension and diabetes. The unexpected findings regarding coping strategies require the clarification of the underlying mechanisms, including the hormonal and immunological aspects.
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Journal Title |
Scientific Reports
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ISSN | 20452322
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Publisher | Springer Nature
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Volume | 12
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Start Page | 291
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Published Date | 2022-01-07
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Rights | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
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DOI (Published Version) | |
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language |
eng
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Publisher
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departments |
Medical Sciences
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