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ID 117821
Title Alternative
T1DM complication in continuous insulin
Author
Masuda, Takafumi Osaka University
Katakami, Naoto Osaka University
Taya, Naohiro Osaka University
Miyashita, Kazuyuki Osaka University
Takahara, Mitsuyoshi Osaka University
Kato, Ken NHO Osaka National Hospital
Shimomura, Iichiro Osaka University
Keywords
Continuous subcutaneous insulin infusion
Diabetic complication
Type 1 diabetes mellitus
Content Type
Journal Article
Description
To evaluate whether continuous subcutaneous insulin infusion attenuates the progression of diabetic complications, we retrospectively extracted data from 35 individuals who had developed type 1 diabetes mellitus aged ≤20 years and whose treatment had been changed from multiple daily injections to continuous subcutaneous insulin infusion. The annual changes in estimated glomerular filtration rate, urinary albumin excretion rate, carotid intima-media thickness and brachial-ankle pulse wave velocity during each treatment period were calculated. Although mean glycated hemoglobin under the continuous subcutaneous insulin infusion treatment was lower than that under the multiple daily injection treatment, there were no significant differences in annual changes in diabetic nephropathy and atherosclerosis between the two treatment periods. This pilot study showed that, in Japanese patients with juvenile-onset type 1 diabetes mellitus, there was no significant difference in the progression of diabetic nephropathy and atherosclerosis, at least in the early stage, between the two treatments.
Journal Title
Journal of Diabetes Investigation
ISSN
20401124
NCID
AA12488319
Publisher
Asian Association for the Study of Diabetes|John Wiley & Sons
Volume
13
Issue
9
Start Page
1528
End Page
1532
Published Date
2022-04-27
Rights
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Institute of Advanced Medical Sciences