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ID 115070
Author
Tsutsumi, Tomohiro Tokushima University
Saitoh, Arisa Tokushima University
Kasai, Tomoyo Tokushima University
Chu, MengYue Tokushima University
Keywords
N,N-Dimethylaminopyridine
1,1,7,7-Tetramethyl-9-azajulolidine
Acylation catalyst
Quinolizidine alkaloid
Cascade reaction
Content Type
Journal Article
Description
1,1,7,7-Tetramethyl-9-azajulolidine (TMAJ), which theoretical studies have suggested as a highly active DMAP analog, was synthesized for the first time. The catalytic activity of TMAJ was confirmed by the acetylation reactions of various tert-alcohols. TMAJ showed much higher catalytic activity than DMAP and one of the highest activity levels among the conventional DMAP analogs. These experimental results were in good agreement with the previous theoretical studies.
Journal Title
Tetrahedron Letters
ISSN
00404039
NCID
AA00861801
AA11539822
Publisher
Elsevier
Volume
61
Issue
26
Start Page
152047
Published Date
2020-05-17
Remark
論文本文は2022-05-17以降公開予定
Rights
© 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
language
eng
TextVersion
その他
departments
Pharmaceutical Sciences