| ID | 110309 |
| Title Transcription | エイヨウ ト メンエキ キノウ : ヒヒッス エイヨウソ テイエイヨウ ジョウタイ カエイヨウ ジョウタイ ト メンエキ
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| Title Alternative | Nutrition and immunity
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| Author |
Sakai, Tohru
Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School
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Nakamoto, Mariko
Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School
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Shuto, Emi
Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School
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Hosaka, Toshio
Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School
|
| Keywords | soy isoflavone
genistein
equol
obesity
T cell
|
| Content Type |
Journal Article
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| Description | It is known that nutritional state crucially affects immune function. In recent years, the contributionof the diet to the optimal working of the immune system has become wildly appreciatedand the influence of different dietary components on specific aspects of immune function has beenextensively studied. Soy isoflavone genistein suppresses antigen-specific immune response inBALB/c mice and suppresses development of atopic-like dermatitis in NC/Nga mice. In other soyisoflavone equol enhances antigen-specific IgE production via IL-13-mediated pathway. Further,equol exacerbates colitis of dextran sulfate sodium-treated mice. Therefore, immune stimulatoryeffects are strikingly different among soy isoflavones. In this reviews, in addition of the isoflavone,we overview the effects of dietary nucleic acid and protein-deficiency on antigen-specific immuneresponses. Furthermore, we present hot topics researches in the field of obesity and T cellfunction.
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| Journal Title |
四国医学雑誌
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| ISSN | 00373699
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| NCID | AN00102041
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| Publisher | 徳島医学会
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| Volume | 66
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| Issue | 1-2
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| Start Page | 19
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| End Page | 26
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| Sort Key | 19
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| Published Date | 2010-04-25
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| EDB ID | |
| FullText File | |
| language |
jpn
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| TextVersion |
Publisher
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| departments |
Medical Sciences
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