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ID 118788
Title Alternative
Impact of frailty in elderly GC patients
Author
Keywords
Gastric cancer
Frailty
Elderly patients
Content Type
Journal Article
Description
Background : Frailty plays a crucial role in cancer patients who have received surgery in this recent aging society. We aimed to investigate frailty as a prognostic factor in elderly gastric cancer (GC) patients who underwent curative gastrectomy. Methods : We analyzed 86 elderly (over 75 years old) GC patients who underwent curative gastrectomy. Patients were assigned to two groups ; frailty group (n = 29) and no-frailty group (n = 57). Clinicopathological values were compared between the two groups. Results : The OS rate of the frailty group was significantly poorer than that of the no-frailty group (5-yr OS rate ; frailty group 52.49% vs. no-frailty group 74.87%, p < 0.05). Multivariate analysis of the OS showed that frailty tended to be significant prognostic factor (p = 0.09). The DFS rate of the frailty group was significantly poorer than that of the no-frailty group (5-yr DFS rate ; frailty group 42.30% vs. no-frailty group 71.55%, p < 0.05). Multivariate analysis of the DFS showed that frailty tended to be significant prognostic factor (p = 0.14). Conclusion : We identified the clinical impact of frailty prognostic factor for elderly GC patients who underwent gastrectomy.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
70
Issue
3-4
Start Page
423
End Page
429
Sort Key
423
Published Date
2023-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
University Hospital