number of access : ?
number of downloads : ?
ID 111172
Title Alternative
大腸内視鏡検査で見逃された結腸進行腺腫と癌の形態学的特徴と部位
Advanced neoplasms after colonoscopy
Author
Kawamura, Takuji Kyoto Second Red Cross Hospital|Tokushima University
Uno, Koji Kyoto Second Red Cross Hospital
Tanaka, Kiyohito Kyoto Second Red Cross Hospital
Ueda, Yuki Kyoto Second Red Cross Hospital
Sakiyama, Naokuni Kyoto Second Red Cross Hospital
Yasuda, Kenjiro Kyoto Second Red Cross Hospital
Keywords
Colorectal cancer
interval cancer
colon polyp
laterally spreading tumor
大腸癌
大腸ポリープ
側方進展型腫瘍
Content Type
Thesis or Dissertation
Description
This retrospective study aimed to clarify the clinical characteristics of advanced colorectal neoplasms after colonoscopy, likely to have been missed on the previous colonoscopy. We reviewed a total of 5,768 consecutive colonoscopies performed from April 2010 to September 2013 in 4,841 patients, and analyzed advanced colorectal neoplasms after colonoscopy, particularly focusing on their morphological characteristics and locations, as compared with primary lesions, defined as lesions detected in their first colonoscopy or in a subsequent colonoscopy >5 years after the previous one. Of the 5,768 examinations, 922 advanced neoplasms (including 217 cancers with≥T2) were detected, and 167 lesions (18.1%) were diagnosed within 5 years after a previous colonoscopy (post-colonoscopy advanced neoplasms). The incidence of right-sided lesions in the post-colonoscopy advanced neoplasms (48.5%, 81/167) was significantly higher than in the primary lesions (34.0%, 257/755 ; p<0.001). We excluded 217 cancers with≥T2 from the morphological analysis to characterize early-stage post-colonoscopy advanced neoplasms. The incidence of non-polypoid lesions in the post-colonoscopy advanced neoplasms (25.6%, 41/160) was significantly higher than that in the primary lesions (12.3%, 67/545 ; p<0.001). These findings suggest that extra attention should be paid to non-polypoid, right-sided advanced colorectal neoplasms during screening and surveillance colonoscopy.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
AA12022913
Publisher
Faculty of Medicine Tokushima University
Volume
63
Issue
3-4
Start Page
163
End Page
170
Sort Key
163
Published Date
2016-08
Remark
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201606101004.pdf
論文本文 : LID201609291003.pdf
本論文は,著者Takuji Kawamuraの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第2957号
Diploma Number
甲医第1290号
Granted Date
2016-03-23
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
Medical Sciences