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ID 111150
Title Alternative
関節リウマチ患者における前足部の切除関節形成術後の足部機能、疾患活動性および能力低下の変化
Changes after forefoot surgery in RA
Author
Sawachika, Fusakazu The University of Tokushima|Utazu Hospital
Uemura, Hirokazu The University of Tokushima KAKEN Search Researchers
Yamaguchi, Miwa The University of Tokushima KAKEN Search Researchers
Bahari, Tirani The University of Tokushima
Miki, Keisuke The University of Tokushima
Todo, Satoshi Utazu Hospital
Inoo, Masayuki Utazu Hospital
Onishi, Ikuko Utazu Hospital
Kurata, Noriyuki Utazu Hospital
Keywords
rheumatoid arthritis
resection arthroplasty of the forefoot
foot function
Content Type
Thesis or Dissertation
Description
The purpose of this study was to investigate the changes in foot function, disease activity, and disability in patients with RA after resection arthroplasty of the forefoot (arthroplasty). Arthroplasty was performed on 11 patients with RA. All study patients underwent clinical assessment to measure disease activity (Disease Activity Score in 28 Joints-C-reactive protein, DAS28-CRP), disability (Health Assessment Questionnaire- Disability Index, HAQ-DI) and foot function (Foot Function Index, FFI) at the following stages : preoperatively and 1, 3, and 12 months after surgery. Following arthroplasty, foot function improved significantly, as assessed by FFI total and subscales (pain, disability, and limitation of activity) (P<0.001, P <0.001, P<0.001, and P=0.002, respectively). Disease activity was significantly improved in relation to DAS28-CRP and its subscales of number of swollen joints and patient global assessment (PtGA) (P=0.033, P=0.008, and P=0.038, respectively). There was no significant difference in disability, as assessed by the HAQ-DI and its subscale, HAQ-walking (P=0.150 and P=0.597, respectively). Foot function improved significantly after arthroplasty, and was maintained at 12 months postoperatively. Additionally, our study showed that disease activity and its subscale PtGA improved after arthroplasty.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
AA12022913
Publisher
Faculty of Medicine Tokushima University
Volume
63
Issue
1-2
Start Page
38
End Page
44
Sort Key
38
Published Date
2016-02
Remark
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201512161004.pdf
論文本文 : LID201603171005.pdf
本論文は,著者Fusakazu Sawachikaの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第2890号
Diploma Number
甲医第1265号
Granted Date
2015-11-26
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
Medical Sciences