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ID 109480
Title Alternative
LIPUSはミニスクリューインプラント周囲の骨形成を促進する
Author
Ganzorig, Khaliunaa Tokushima University
Maeda, Yuichi Tokushima University
Mansjur, Karima Tokushima University
Sato, Minami Tokushima University
Nagata, Kumiko Tokushima University
Keywords
Low-intensity pulsed ultrasound
miniscrew implant
bone formation
stainless steel and titanium
Content Type
Thesis or Dissertation
Description
Miniscrew implants (MSIs) are currently used to provide absolute anchorage in orthodontics; however, their initial stability is an issue of concern. Application of low-intensity pulsed ultrasound (LIPUS) can promote bone healing. Therefore, LIPUS application may stimulate bone formation around MSIs and enhance their initial stability. Aim. To investigate the effect of LIPUS exposure on bone formation after implantation of titanium (Ti) and stainless steel (SS) MSIs. Methods. MSIs made of Ti-6Al-4V and 316L SS were placed on rat tibiae and treated with LIPUS. The bone morphology around MSIs was evaluated by scanning electron microscopy and threedimensional micro-computed tomography. MC3T3-E1 cells cultured on Ti and SS discs were treated with LIPUS, and the temporary expression of alkaline phosphatase (ALP) was examined. Results. Bone-implant contact increased gradually from day 3 to day 14 after MSI insertion. LIPUS application increased the cortical bone density, cortical bone thickness, and cortical bone rate after implantation of Ti and SS MSIs (P < 0.05). LIPUS exposure induced ALP upregulation in MC3T3- E1 cells at day 3 (P < 0.05). Conclusion. LIPUS enhanced bone formation around Ti and SS MSIs, enhancing the initial stability of MSIs.
Journal Title
Archives of Oral Biology
ISSN
00039969
NCID
AA00548457
AA11521918
Publisher
Elsevier
Volume
60
Issue
6
Start Page
902
End Page
910
Published Date
2015-03-04
Remark
内容要旨・審査要旨・論文本文の公開:
内容要旨 : LID201509181001.pdf
審査要旨 : LID201509181002.pdf
論文本文 : k2863_fulltext.pdf
著者の申請により要約(2015-09-18公開)に替えて論文全文を公開(2019-06-10)
本論文は, 著者Khaliunaa Ganzorigの学位論文として提出され, 学位審査・授与の対象となっている。
Rights
© 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第2863号
Diploma Number
甲口第402号
Granted Date
2015-09-16
Degree Name
Doctor of Dental Science
Grantor
Tokushima University
departments
Oral Sciences