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ID 114812
Title Alternative
Skeletal muscle mass and vitamin D
Author
Sato, Michiko Kenshokai Gakuen College for Health and Welfare
Morishita, Teruhiro Kenshokai Gakuen College for Health and Welfare
Katayama, Takafumi University of Hyogo
Satomura, Shigeko Tokushima Prefectural Hinomine Medical Center for the Handicapped
Okuno, Hiroko Kenshokai Gakuen College for Health and Welfare
Sumida, Nami Kenshokai Gakuen College for Health and Welfare
Sakuma, Masae Sugiyama Jogakuen University
Arai, Hidekazu The University of Shizuoka
Kawaura, Akihiko Kenshokai Gakuen College for Health and Welfare
Keywords
Skeletal muscle mass
24-h urinary creatinine method
serum 25-hydroxyvitamin D level
walking difficulty
intestinal absorption rate
Content Type
Journal Article
Description
A clearer understanding of skeletal muscle mass (SMM) in middle-aged and elderly individuals is important for maintaining functionality. In the present study, age-related changes in SMM, the threshold of SMM with walking difficulty, intestinal nutrient absorption rate, and various serum factors were examined in Japanese populations of different ages. We used 24-h creatinine excretion as a measure of total body SMM. Age-related decreases in SMM, intestinal nutrient absorption rates, and serum 25-hydroxyvitamin D [25(OH)D] concentrations were significantly higher in women than in men. The cut-off values for SMM (kg), its percentage of total body weight (BW), the SMM index [SMMI] (Kg / m2), and creatinine height index (CHI) (%) in elderly individuals with walking difficulty were approximately 8-10 kg, 17-20% of BW, 3.9-4.6 kg / m2, and 44%, respectively. Serum 25(OH)D concentrations were closely associated with SMM (kg, % of BW, kg / m2) and CHI (%) as well as the intestinal absorption rates of nitrogen (%) and phosphorus (%) in women, but not in men. The present results demonstrate that vitamin D is an important metabolic factor in skeletal muscle, and contributes to the optimal management of skeletal muscle and the prevention of sarcopenia.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA12022913
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
67
Issue
1-2
Start Page
151
End Page
157
Sort Key
151
Published Date
2020-02
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital
Medical Sciences