Dietary Pattern and Metabolic Syndrome
Bahari, Tirani Tokushima University
Uemura, Hirokazu Tokushima University KAKEN Search Researchers
Katsuura-Kamano, Sakurako Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yamaguchi, Miwa Tokushima University KAKEN Search Researchers
Nakamoto, Mariko Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Miki, Keisuke Tokushima University
Ishizu, Masashi Tokushima University
Reduced rank regression
Thesis or Dissertation
Background: Nutrients have been proposed to be related to metabolic syndrome (MetS). The aims of this study were to identify dietary patterns that correlated with several nutrients using reduced rank regression (RRR) and to examine the association between extracted dietary patterns and prevalence of MetS in a Japanese population.
Methods: The study population comprised 1,092 Japanese men and women (35–69 years old) who had participated in the baseline survey of the Japan Multi-Institutional Collaborative Cohort Study in Tokushima Prefecture. Dietary patterns were derived with RRR using 46 food items as predictors and six established nutrients (potassium, calcium, vitamin D, vitamin C, insoluble dietary fiber, and carotene) as response variables. Associations between extracted dietary patterns and MetS were then examined with logistic regression models.
Results: Among the six dietary patterns, dietary pattern 1 (DP1) explained the largest proportion (60.1%) of variance in the six nutrients. Therefore, only DP1 was selected for further analysis. DP1 was characterized by high intake frequency of vegetables, fruits, fish and small fish, natto (fermented soybeans), and deep-fried tofu. After adjustment for potential confounders, significant inverse associations were found between DP1 score and MetS (odds ratio [OR] for each quartile: 1.00, 0.58, 0.60, 0.52; Ptrend = 0.02); DP1 and high blood pressure (Ptrend = 0.0002); and DP1 and high blood glucose (Ptrend = 0.02).
Conclusion: A dietary pattern characterized by high intake of vegetables, fruits, fish and small fish, natto, and deep-fried tofu was associated with reduced prevalence of MetS in a Japanese population.
Journal of Epidemiology
Japan Epidemiological Association
本論文は, 著者Tirani Bahariの学位論文として提出され, 学位審査・授与の対象となっている。
Copyright © 2017 Tirani Bahari et al. This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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|MEXT report number||
Doctor of Medical Science