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Shigenaga, Akira

Published Date (desc)
Residue-selective C−H sulfenylation enabled by acid-activated S-acetamidomethyl cysteine sulfoxide with application to one-pot stapling and lipidation sequence
Author Ohkawachi, Kento/ Anzaki, Kaito/ Kobayashi, Daishiro/ Kyan, Ryuji/ Yasuda, Takuma/ Denda, Masaya/ Harada, Norio/ Shigenaga, Akira/ Inagaki, Nobuya/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemistry- A European Journal
Volume 29
Issue 26
Published Date 2023-03-15
departments Pharmaceutical Sciences
Development of a novel tocopheryl ester for suppression of lipid accumulation without cytotoxicity by optimization of dicarboxylic ester moiety
Author Yamasaki, Misaki/ Seto, Yuika/ Ozono, Mizune/ Nakao, Michiyasu/ Shigenaga, Akira/ Otaka, Akira/ Sano, Shigeki/ Kogure, Kentaro/
Content Type Journal Article
Journal Title Biochemistry and Biophysics Reports
Volume 31
Published Date 2022-08-16
departments Pharmaceutical Sciences
Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells
Author Miyake, Masato/ Sobajima, Mitsuaki/ Kurahashi, Kiyoe/ Shigenaga, Akira/ Denda, Masaya/ Otaka, Akira/ Saio, Tomohide/ Sakane, Naoki/ Kosako, Hidetaka/ Oyadomari, Seiichi/
Content Type Journal Article
Journal Title Cell Chemical Biology
Volume 29
Issue 6
Published Date 2022-02-09
departments Institute of Advanced Medical Sciences University Hospital Pharmaceutical Sciences
Late-stage macrolactonisation enabled by tandem acyl transfers followed by desulphurisation
Author Sato, Daiki/ Denda, Masaya/ Tsunematsu, Honoka/ Tanaka, Naonobu/ Konishi, Isamu/ Komiya, Chiaki/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical Communications
Volume 58
Issue 17
Published Date 2022-02-01
departments Pharmaceutical Sciences Bioscience and Bioindustry
Deprotection of S-Acetamidomethyl Cysteine with Copper (II) and 1,2-Aminothiols under Aerobic Conditions
Author Kobayashi, Daishiro/ Naruse, Naoto/ Denda, Masaya/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic & Biomolecular Chemistry
Volume 18
Issue 42
Published Date 2020-08-20
departments Pharmaceutical Sciences
Sulfanylmethyldimethylaminopyridine as a Useful Thiol Additive for Ligation Chemistry in Peptide/Protein Synthesis
Author Ohkawachi, Kento/ Kobayashi, Daishiro/ Morimoto, Kyohei/ Shigenaga, Akira/ Denda, Masaya/ Yamatsugu, Kenzo/ Kanai, Motomu/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic Letters
Volume 22
Issue 14
Published Date 2020-05-12
departments Pharmaceutical Sciences
Development of Chemical Biology Tools Focusing on Peptide/Amide Bond Cleavage Reaction
Author Shigenaga, Akira/
Content Type Journal Article
Journal Title Chemical and Pharmaceutical Bulletin
Volume 67
Issue 11
Published Date 2019-11-01
departments Pharmaceutical Sciences
Asymmetric Synthesis of α‐Amino Phosphonic Acids using Stable Imino Phosphonate as a Universal Precursor
Author Inokuma, Tsubasa/ Sakakibara, Takuya/ Someno, Takatoshi/ Masui, Kana/ Shigenaga, Akira/ Otaka, Akira/ Yamada, Ken-ichi/
Content Type Journal Article
Journal Title Chemistry- A European Journal
Volume 25
Issue 60
Published Date 2019-08-26
departments Pharmaceutical Sciences
Traceless synthesis of protein thioesters using enzyme-mediated hydrazinolysis and subsequent self-editing of cysteinyl prolyl sequence
Author Komiya, Chiaki/ Shigenaga, Akira/ Tsukimoto, Jun/ Ueda, Masahiro/ Morisaki, Takuya/ Inokuma, Tsubasa/ Itoh, Kohji/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical Communications
Volume 55
Issue 49
Published Date 2019-05-23
departments Pharmaceutical Sciences
スクリプス研究所Janda研への留学経験を振り返る
Author Shigenaga, Akira/
Content Type Journal Article
Journal Title Journal of the Pharmaceutical Society of Japan
Volume 139
Issue 2
Published Date 2019-02-01
departments Pharmaceutical Sciences
A recyclable hydrophobic anchor-tagged asymmetric amino thiourea catalyst
Author Jichu, Takahisa/ Inokuma, Tsubasa/ Aihara, Keisuke/ Kohiki, Taiki/ Nishida, Kodai/ Shigenaga, Akira/ Yamada, Ken-ichi/ Otaka, Akira/
Content Type Journal Article
Journal Title ChemCatChem
Volume 10
Issue 16
Published Date 2018-07-11
departments Pharmaceutical Sciences
Light-induced propulsion of a giant liposome driven by peptide nanofibre growth
Author Inaba, Hiroshi/ Uemura, Akihito/ Morishita, Kazushi/ Kohiki, Taiki/ Shigenaga, Akira/ Otaka, Akira/ Matsuura, Kazunori/
Content Type Journal Article
Journal Title Scientific Reports
Volume 8
Published Date 2018-04-19
departments Pharmaceutical Sciences
Resin-Bound Crypto-Thioester for Native Chemical Ligation
Author Naruse, Naoto/ Ohkawachi, Kento/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic Letters
Volume 20
Issue 8
Published Date 2018-04-09
departments Pharmaceutical Sciences
Effect of Phosphatidylserine and Cholesterol on Membrane-mediated Fibril Formation by the N-terminal Amyloidogenic Fragment of Apolipoprotein A-I
Author Mizuguchi, Chiharu/ Nakamura, Mitsuki/ Kurimitsu, Naoko/ Ohgita, Takashi/ Nishitsuji, Kazuchika/ Baba, Teruhiko/ Shigenaga, Akira/ Shimanouchi, Toshinori/ Okuhira, Keiichiro/ Otaka, Akira/ Saito, Hiroyuki/
Content Type Journal Article
Journal Title Scientific Reports
Volume 8
Published Date 2018-04-03
departments Medical Sciences Pharmaceutical Sciences
ProteoFind : A script for finding proteins that are suitable for chemical synthesis
Author Shigenaga, Akira/ Naruse, Naoto/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 74
Issue 19
Published Date 2018-03-15
departments Pharmaceutical Sciences
Chemical Synthetic Platform for Chlorpromazine Oligomers That Were Reported as Photo-degradation Products of Chlorpromazine
Author Kohiki, Taiki/ Nishikawa, Yusuke/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical and Pharmaceutical Bulletin
Volume 65
Issue 12
Published Date 2017-12-01
departments Pharmaceutical Sciences
CXCL14 Acts as a Specific Carrier of CpG DNA into Dendritic Cells and Activates Toll-like Receptor 9-mediated Adaptive Immunity
Author Tanegashima, Kosuke/ Takahashi, Rena/ Nuriya, Hideko/ Iwase, Rina/ Naruse, Naoto/ Tsuji, Kohei/ Shigenaga, Akira/ Otaka, Akira/ Hara, Takahiko/
Content Type Journal Article
Journal Title EBioMedicine
Volume 24
Published Date 2017-09-14
departments Pharmaceutical Sciences
Cysteine-Free Intramolecular Ligation of N-Sulfanylethylanilide Peptide Using 4-Mercaptobenzylphosphonic Acid : Synthesis of Cyclic Peptide Trichamide
Author Aihara, Keisuke/ Inokuma, Tsubasa/ Jichu, Takahisa/ Lin, Zhenjian/ Fu, Feixue/ Yamaoka, Kosuke/ Shigenaga, Akira/ Hutchins, David A./ Schmidt, Eric W./ Otaka, Akira/
Content Type Journal Article
Journal Title Synlett
Volume 28
Issue 15
Published Date 2017-07-06
departments Pharmaceutical Sciences
Elucidation of inhibitor-binding pockets of D-amino acid oxidase using docking simulation and N-sulfanylethylanilide-based labeling technology
Author Kohiki, Taiki/ Kato, Yusuke/ Nishikawa, Yusuke/ Yorita, Kazuko/ Sagawa, Ikuko/ Denda, Masaya/ Inokuma, Tsubasa/ Shigenaga, Akira/ Fukui, Kiyoshi/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic & Biomolecular Chemistry
Volume 15
Issue 25
Published Date 2017-05-05
departments Institute of Advanced Medical Sciences Technical Support Department Pharmaceutical Sciences
Invention of stimulus‐responsive peptide‐bond‐cleaving residue (Spr) and its application to chemical biology tools
Author Shigenaga, Akira/ Yamamoto, Jun/ Kohiki, Taiki/ Inokuma, Tsubasa/ Otaka, Akira/
Content Type Journal Article
Journal Title Journal of Peptide Science
Volume 23
Issue 7-8
Published Date 2017-01-19
departments Pharmaceutical Sciences
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