ID | 111620 |
Author |
Okahisa, Toshiya
The University of Tokushima
Tokushima University Educator and Researcher Directory
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Sogabe, Masahiro
The University of Tokushima
Tokushima University Educator and Researcher Directory
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Hayashi, Shigehito
The University of Tokushima
Shibata, Hiroshi
The University of Tokushima
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Keywords | contrast medium
iomeprol
hemofiltration
hemodiafiltration
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Content Type |
Journal Article
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Description | The contrast medium-removing effect of hemofiltration (HF) and hemodiafiltration (HDF) was experimentally investigated using a bovine blood tank model. HF and HDF were performed at a blood flow rate of 100ml/min with a polysulfone hemofilter (PS filter-CF ; membrane area : 0.7 m2). Two hundred milliliters of iomeprol (300 mgI/ml) was administered by a single injection into 4 liters of bovine blood. The blood half-lives of iomeprol were 1.0 hr for the high flow rate HDF group [replacement fluid flow rate (QF) : 10 ml/min and dialysate flow rate (QD) : 40 ml/min], 1.8 hr for the HDF group (QF : 10 ml/min and QD : 10 ml/min), and 3.8 hr for the HF group (QF : 10 ml/min). The mean clearance rates were 39.7 ml/min for the high flow rate HDF group, 21.4 ml/min for the HDF group, and 12.0 ml/min for the HF group. Iomeprol was mostly excreted in the waste fluid. It is concluded that HDF can remove contrast media more effectively than HF.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13431420
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NCID | AA11166929
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Publisher | The University of Tokushima School of Medicine
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Volume | 45
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Issue | 1-4
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Start Page | 87
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End Page | 93
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Sort Key | 87
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Published Date | 1998-08
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EDB ID | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
Medical Sciences
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