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ID 118071
Author
Sogabe, Masahiro Tokushima University|Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Okahisa, Toshiya Tokushima University|Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kagawa, Miwako Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers
Ueda, Hiroyuki Tokushima University|Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers
Kagemoto, Kaizo Tokushima University
Nakasono, Masahiko Tsurugi Municipal Handa Hospital
Keywords
erosive esophagitis
alcohol intake
development
sex
age
Content Type
Journal Article
Description
The influence of changes in alcohol consumption on erosive esophagitis (EE) development in both sexes is unclear. This observational study investigated sex differences in the influence of alcohol consumption on EE development, and included 2582 patients without EE at baseline from 13,448 patients who underwent >2 health check-ups over >1 year. The rates of non-drinkers who started drinking, and drinkers who abstained from drinking, who increased, and who decreased their weekly alcohol consumption were 7.2%, 9.7%, 14.7%, and 24.1% and 7.3%, 17.8%, 12.8%, and 39.0% in men and women, respectively. In the final cohort, 211/1405 (15.0%) men and 79/1177 (6.7%) women newly developed EE. The odds ratio (OR) for drinking in EE development was 1.252 (95% confidence interval (CI), 0.907–1.726) among men and 1.078 (95% CI, 0.666–1.747) among women. Among men aged <50 years, the OR for drinking ≥70 g/week in EE development was 2.825 (95% CI, 1.427–5.592), whereas among women, the OR for drinking ≥140 g/week in EE development was 3.248 (95% CI, 1.646–6.410). Among participants aged <50 years, the OR for daily drinking in EE development was 2.692 (95% CI, 1.298–5.586) among men and 4.030 (95% CI, 1.404–11.57) among women. The influence of alcohol consumption on EE development differed between the sexes. We recommend no alcohol consumption for individuals aged <50 years to avoid EE development. Daily drinkers should be assessed for EE development.
Journal Title
Nutrients
ISSN
20726643
Publisher
MDPI
Volume
14
Issue
22
Start Page
4760
Published Date
2022-11-10
Rights
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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language
eng
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departments
Medical Sciences
University Hospital