Colon Hypoperfusion After Artery Ligation
Kono, Toru The University of Tokushima|Sapporo Higashi Tokushukai Hospital
Shimada, Mitsuo The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sugitani, Ayumu Sapporo Higashi Tokushukai Hospital
Kashihara, Hideya The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Takasu, Chie The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Nishi, Masaaki The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Tokunaga, Takuya The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yoshikawa, Kozo The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
anterior rectal resection
Background: Anastomotic leakage (AL) after colorectal surgery is associated with insufficient vascular perfusion of the anastomotic ends. This study aimed to evaluate the effect of high vs. low ligation of the ileocolic artery and inferior mesenteric artery, respectively, on the vascular perfusion of the bowel stumps during ileocecal resection (ICR) and anterior rectal resection (AR).
Methods: We retrospectively evaluated patients who underwent ICR or AR between 2016 and 2020. Real-time indocyanine green fluorescence angiography was performed to measure the fluorescence time (FT) as a marker of the blood flow in the proximal and distal stumps before anastomosis.
Results: Thirty-four patients with lower right-sided colon cancer underwent laparoscopic ICR. Forty-one patients with rectosigmoid colon or rectal cancer underwent robotic high AR (HAR) (n = 8), robotic low AR (LAR) (n = 6), laparoscopic HAR (n = 8), or laparoscopic LAR (n = 19). The FT was similar in the ileal and ascending colon stumps (p = 1.000) and did not differ significantly between high vs. low ligation of the ileocolic artery (p = 0.934). The FT was similar in the sigmoid colon and rectal stumps (p = 0.642), but high inferior mesenteric artery ligation significantly prolonged FT in the sigmoid colon during AR compared with low ligation (p = 0.004), indicating that the high ligation approach caused significant hypoperfusion compared with low ligation. The AL rate was similar after low vs. high ligation.
Conclusions: Low vascular perfusion of the bowel stumps may not be an absolute risk factor for AL. High inferior mesenteric artery ligation could induce sigmoid colon stump hypoperfusion during anterior rectal resection.
Frontiers in Surgery
Frontiers Media S.A.
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