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Liquid-Phase Synthesis of Bridged Peptides Using Olefin Metathesis of a Protected Peptide with a Long Aliphatic Chain Anchor

Author	Aihara, Keisuke/ Komiya, Chiaki/ Shigenaga, Akira/ Inokuma, Tsubasa/ Takahashi, Daisuke/ Otaka, Akira/
Content Type	Journal Article
Journal Title	Organic Letters
Volume	17
Issue	3
Published Date	2015-01-28
departments	Pharmaceutical Sciences

Resin-Bound Crypto-Thioester for Native Chemical Ligation

Author	Naruse, Naoto/ Ohkawachi, Kento/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type	Journal Article
Journal Title	Organic Letters
Volume	20
Issue	8
Published Date	2018-04-09
departments	Pharmaceutical Sciences

Cysteine-Free Intramolecular Ligation of N-Sulfanylethylanilide Peptide Using 4-Mercaptobenzylphosphonic Acid : Synthesis of Cyclic Peptide Trichamide

Author	Aihara, Keisuke/ Inokuma, Tsubasa/ Jichu, Takahisa/ Lin, Zhenjian/ Fu, Feixue/ Yamaoka, Kosuke/ Shigenaga, Akira/ Hutchins, David A./ Schmidt, Eric W./ Otaka, Akira/
Content Type	Journal Article
Journal Title	Synlett
Volume	28
Issue	15
Published Date	2017-07-06
departments	Pharmaceutical Sciences

Intracellular localization and binding partners of death associated protein kinase-related apoptosis-inducing protein kinase 1

Author	Oue, Yuna/ Murakami, Sara/ Isshiki, Kinuka/ Tsuji, Akihiko/ Yuasa, Keizo/
Content Type	Journal Article
Journal Title	Biochemical and Biophysical Research Communications
Volume	496
Issue	4
Published Date	2018-01-31
departments	Bioscience and Bioindustry

Type II cGMP-dependent protein kinase negatively regulates fibroblast growth factor signaling by phosphorylating Raf-1 at serine 43 in rat chondrosarcoma cells

Author	Kamemura, Norio/ Murakami, Sara/ Komatsu, Hiroaki/ Sawanoi, Masahiro/ Miyamoto, Kenji/ Ishidoh, Kazumi/ Kishimoto, Koji/ Tsuji, Akihiko/ Yuasa, Keizo/
Content Type	Journal Article
Journal Title	Biochemical and Biophysical Research Communications
Volume	483
Issue	1
Published Date	2017-01-03
departments	Bioscience and Bioindustry

Alisol B, a triterpene from Alismatis rhizoma (dried rhizome of Alisma orientale), inhibits melanin production in murine B16 melanoma cells

Author	Yoshida, Ichiro/ Ito, Chihiro/ Matsuda, Shinya/ Tsuji, Akihiko/ Yanaka, Noriyuki/ Yuasa, Keizo/
Content Type	Journal Article
Journal Title	Bioscience, Biotechnology, and Biochemistry
Volume	81
Issue	3
Published Date	2017-01-04
departments	Bioscience and Bioindustry

Labelling of Endogenous Target Protein via N–S Acyl Transfer-Mediated Activation of N-Sulfanylethylanilide

Author	Denda, Masaya/ Morisaki, Takuya/ Kohiki, Taiki/ Yamamoto, Jun/ Sato, Kohei/ Sagawa, Ikuko/ Inokuma, Tsubasa/ Sato, Youichi/ Yamauchi, Aiko/ Shigenaga, Akira/ Otaka, Akira/
Content Type	Journal Article
Journal Title	Organic & Biomolecular Chemistry
Volume	14
Issue	26
Published Date	2016-05-31
departments	Technical Support Department Pharmaceutical Sciences

Synthesis of lactam-bridged cyclic peptides using sequential olefin metathesis and diimide reduction reactions

Author	Aihara, Keisuke/ Inokuma, Tsubasa/ Komiya, Chiaki/ Shigenaga, Akira/ Otaka, Akira/
Content Type	Journal Article
Journal Title	Tetrahedron
Volume	71
Issue	24
Published Date	2015-05-01
departments	Pharmaceutical Sciences

Development of a Chemical Methodology for the Preparation of Peptide Thioesters Applicable to Naturally Occurring Peptides Using a Sequential Quadruple Acyl Transfer System

Author	Tsuda, Yusuke/ Shigenaga, Akira/ Tsuji, Kohei/ Denda, Masaya/ Sato, Kohei/ Kitakaze, Keisuke/ Nakamura, Takahiro/ Inokuma, Tsubasa/ Itoh, Kohji/ Otaka, Akira/
Content Type	Journal Article
Journal Title	ChemistryOpen
Volume	4
Issue	4
Published Date	2015-04-28
departments	Pharmaceutical Sciences

The total chemical synthesis of the monoglycosylated GM2 ganglioside activator using a novel cysteine surrogate

Author	Sato, Kohei/ Kitakaze, Keisuke/ Nakamura, Takahiro/ Naruse, Naoto/ Aihara, Keisuke/ Shigenaga, Akira/ Inokuma, Tsubasa/ Tsuji, Daisuke/ Itoh, Kohji/ Otaka, Akira/
Content Type	Journal Article
Journal Title	Chemical Communications
Volume	51
Issue	49
Published Date	2015-05-13
departments	Pharmaceutical Sciences

PCTK3/CDK18 regulates cell migration and adhesion by negatively modulating FAK activity

Author	Matsuda, Shinya/ Kawamoto, Kohei/ Miyamoto, Kenji/ Tsuji, Akihiko/ Yuasa, Keizo/
Content Type	Journal Article
Journal Title	Scientific Reports
Volume	7
Published Date	2017-03-31
departments	Bioscience and Bioindustry

Tailored Synthesis of 162-Residue S-Monoglycosylated GM2-Activator Protein (GM2AP) Analogues that Allows Facile Access to Protein Library

Author	Nakamura, Takahiro/ Sato, Kohei/ Naruse, Naoto/ Kitakaze, Keisuke/ Inokuma, Tsubasa/ Hirokawa, Takatsugu/ Shigenaga, Akira/ Itoh, Kohji/ Otaka, Akira/
Content Type	Journal Article
Journal Title	ChemBioChem
Volume	17
Issue	20
Published Date	2016-08-19
departments	Pharmaceutical Sciences

Development of an Anilide-Type Scaffold for the Thioester Precursor N-Sulfanylethylcoumarinyl Amide

Author	Eto, Mitsuhiro/ Naruse, Naoto/ Morimoto, Kyohei/ Yamaoka, Kosuke/ Sato, Kohei/ Tsuji, Kohei/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type	Journal Article
Journal Title	Organic Letters
Volume	18
Issue	17
Published Date	2016-08-16
departments	Pharmaceutical Sciences

Identification and Characterization of a 25 kDa Protein That Is Indispensable for the Efficient Saccharification of Eisenia bicyclis in the Digestive Fluid of Aplysia kurodai

Author	Tsuji, Akihiko/ Kuwamura, Shuji/ Shirai, Akihiro/ Yuasa, Keizo/
Content Type	Journal Article
Journal Title	PLOS ONE
Volume	12
Issue	1
Published Date	2017-01-27
departments	Bioscience and Bioindustry

The Novel Monoclonal Antibody 9F5 Reveals Expression of a Fragment of GPNMB/Osteoactivin Processed by Furin-like Protease(s) in a Subpopulation of Microglia in Neonatal Rat Brain

Author	Kawahara, Kohichi/ Hirata, Hiroshi/ Ohbuchi, Kengo/ Nishi, Kentaro/ Maeda, Akira/ Kuniyasu, Akihiko/ Yamada, Daisuke/ Maeda, Takehiko/ Tsuji, Akihiko/ Sawada, Makoto/ Nakayama, Hitoshi/
Content Type	Journal Article
Journal Title	GLIA
Volume	64
Issue	11
Published Date	2016-07-27
departments	Bioscience and Bioindustry

Facile Guanidine Formation under Mild Acidic Conditions

Author	Takeuchi, Kohei/ Nakayama, Atsushi/ Tanino, Keiji/ Namba, Kosuke/
Content Type	Journal Article
Journal Title	Synlett
Volume	27
Issue	18
Published Date	2016-08-01
departments	Pharmaceutical Sciences

Functional 1,3a,6a-triazapentalene scaffold : Design of fluorescent probes for kinesin spindle protein (KSP)

Author	Sawada, Jun-ichi/ Osawa, Ayumi/ Takeuchi, Tomoki/ Kaneda, Masato/ Oishi, Shinya/ Fujii, Nobutaka/ Asai, Akira/ Tanino, Keiji/ Namba, Kosuke/
Content Type	Journal Article
Journal Title	Bioorganic & Medicinal Chemistry Letters
Volume	26
Issue	23
Published Date	2016-10-15
departments	Pharmaceutical Sciences

Development of 1,3a,6a-triazapentalene-labeled enterobactin as a fluorescence quenching sensor of iron ion

Author	Hayashi, Tsukiho/ Osawa, Ayumi/ Watanabe, Takehiro/ Murata, Yoshiko/ Nakayama, Atsushi/ Namba, Kosuke/
Content Type	Journal Article
Journal Title	Tetrahedron Letters
Volume	58
Issue	20
Published Date	2017-04-05
departments	Pharmaceutical Sciences

プロテアソームの活性化因子PA28ファミリーの分子的性質とγ-インターフェロンによる調節機構

Author	Tanahashi, Nobuyuki/
Content Type	Journal Article
Journal Title	Shikoku Acta Medica
Volume	53
Issue	1
Published Date	1997-02-25

体性感覚誘発電位(SEP)および脳波へのdiazepamとsodium valproateの急性効果

Author	Hanano, Motonori/ Matsuoka, Koji/ Tomotake, Masahito/ Kihara, Shoichi/ Ikuta, Takumi/
Content Type	Journal Article
Journal Title	Shikoku Acta Medica
Volume	53
Issue	1
Published Date	1997-02-25
departments	Medical Sciences