多彩な臨床所見と複数の症候群を合併した興味ある稀な１例

A ５４-year-old woman consulted our clinic to complain of urticaria and Raynoud’s phenomenon, and she suffered from Sjogren’s syndrome and postoperative hypothyroidism due to thyroid cancer （Antithyroid antibody were negative）. This case who had clinical symptoms of obesity, headache, and hypotension was diagnosed CREST syndrome （Anticentromere antibody was strongly positive, but Anti-Scl ７０ antibody was negative） to be incorporated empty sella syndrome with hypo-ACTH-nemia, hypo-TSH-nemia and hyper-PRL-nemia respectively, but visual disturbance or hypertension were not accompanied. Further it was probably suspected autoimmune fatigue syndrome and Fibromyalgia to be noticed with general fatigue and polymyalgia, taken together it was thought that hypokalemia and hypomagnesiumnemia was needed to discriminate the complications of renal tubular acidosis with Sjogren’s syndrome.
From these results, a rare case who was indicated primary Sjogren’s syndrome, CREST syndrome, Empty sella syndrome with pituitary dysfunctions and suspected autoimmune fatigue syndrome was reported.

四国医学雑誌 : http://www.tokushima-u.ac.jp/med/research/shikoku_acta_medica.html