ID | 109381 |
Title Alternative | さまざまな身体活動レベルにおけるヒトの骨格筋量と筋力に対する食事性大豆たんぱく質の効果
Effect of soy protein on the muscle in human
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Author |
Hashimoto, Rie
The University of Tokushima
Sakai, Atsuko
The University of Tokushima
Murayama, Masumi
The University of Tokushima
Ochi, Arisa
The University of Tokushima
Ohno, Ayako
The University of Tokushima
Yanagawa, Hiroaki
Tokushima University
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Yasui, Natsuo
Tokushima University
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Inatsugi, Mikiko
Inatsugi Orthopedic Hospital
Doi, Daisuke
Inatsugi Orthopedic Hospital
Takeda, Masanori
Kyoritsu Hospital
Mukai, Rie
The University of Tokushima
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Terao, Junji
The University of Tokushima
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Nikawa, Takeshi
The University of Tokushima
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Keywords | bedridden patients
casein
muscle volume
quadriceps femoris muscle
soy protein isolate
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Content Type |
Thesis or Dissertation
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Description | Background : In recent years, the number of bedridden people is rapidly increasing due to aging or lack of exercise in Japan. This problem is becoming more serious, since there is no countermeasure against it. In the present study, we designed to investigate whether dietary proteins, especially soy, had beneficial effects on skeletal muscle in 59 volunteers with various physical activities. Methods : We subjected 59 volunteers with various physical activities to meal intervention examination. Persons with low and high physical activities were divided into two dietary groups, the casein diet group and the soy diet group. They ate daily meals supplemented with 7.8 g of powdered casein or soy protein isolate every day for 30 days. Bedridden patients in hospitals were further divided into three dietary groups : the no supplementation diet group, the casein diet group and the soy diet group. They were also subjected to a blood test, a urinalysis, magnetic resonance imaging analysis and muscle strength test of the knee before and after the meal intervention study. Results : Thirty-day soy protein supplementation significantly increased skeletal muscle volume in participants with low physical activity, compared with 30-day casein protein supplementation. Both casein and soy protein supplementation increased the volume of quadriceps femoris muscle in bedridden patients. Consistently, soy protein significantly increased their extension power of the knee, compared with casein protein. Although casein protein increased skeletal muscle volume more than soy protein in bedridden patients, their muscle strength changes by soy protein supplementation were bigger than those by casein protein supplementation. Conclusions : The supplementation of soy protein would be one of the effective foods which prevent the skeletal muscle atrophy caused by immobilization or unloading.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA12022913
AA11166929
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Publisher | Tokushima University Faculty of Medicine
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Volume | 62
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Issue | 3-4
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Start Page | 177
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End Page | 183
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Sort Key | 177
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Published Date | 2015-08
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Remark | 内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201505251027.pdf 論文本文 : k2851_fulltext.pdf 本論文は,著者Rie Hashimotoの学位論文として提出され, 学位審査・授与の対象となっている。 著者の申請により要約(2015-05-26公開)に替えて論文全文を公開(2020-04-10) |
EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
ETD
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MEXT report number | 甲第2851号
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Diploma Number | 甲栄第229号
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Granted Date | 2015-03-26
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Degree Name |
Doctor of Nutritional Science
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Grantor |
Tokushima University
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departments |
Medical Sciences
University Hospital
Bioscience and Bioindustry
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