| ID | 109862 |
| Title Transcription | エンショウ カンキョウ ニヨル シズイ サイボウ ノ カンサイボウカ : シズイ サイボウ ブンカ ニ アタエル シュヨウ エシ インシ TNF-α ノ エイキョウ
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| Title Alternative | Reprogramming of Human Dental Pulp Cells Mediated by Inflammatory Signals : Effects of TNF-α on Human Dental Pulp Cell Differentiation
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| Author |
Ueda, Mayu
Department of Stomatognathic Function and Occlusal Reconstruction, Tokushima University Graduate School, Institute of Biomedical Sciences
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| Keywords | 歯髄細胞
TNF-α
幹細胞化
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| Content Type |
Journal Article
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| Description | During normal pulp tissue healing, inflammatory cytokines, such as tumor necrosis factoralpha (TNF-α) or interleukins, act in the initial 48 hours (inflammatory phase) and play important roles not only as chemo-attractants of inflammatory cells and stem/progenitor cells but also in inducing a cascade of reactions toward tissue regeneration or reparative dentin formation or both. Previous reports have shown that inflammatory cytokines regulate the differentiation capacity of dental pulp stem/progenitor cells (DPCs), but none has interrogated the impact of these cytokines on the stem cell phenotype of stem/progenitor cells.
In this review, I would like to summarize about the effects of a short-term treatment with TNF-α on the stem cell phenotype and differentiation ability of human DPCs. |
| Journal Title |
Journal of Oral Health and Biosciences
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| ISSN | 21887888
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| NCID | AA12713630
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| Publisher | 四国歯学会
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| Volume | 28
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| Issue | 1
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| Start Page | 1
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| End Page | 7
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| Sort Key | 1
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| Published Date | 2015-07-10
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| Remark | 7月発行だが、6月号である。
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| EDB ID | |
| FullText File | |
| language |
jpn
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| TextVersion |
Publisher
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| departments |
University Hospital
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