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ID 110830
Author
Seike, Junichi Department of Oncological and Regenerative Surgery, Institute of Health Bioscience, The University of Tokushima Graduate School
Yoshida, Takahiro Department of Oncological and Regenerative Surgery, Institute of Health Bioscience, The University of Tokushima Graduate School KAKEN Search Researchers
Honda, Junko Department of Oncological and Regenerative Surgery, Institute of Health Bioscience, The University of Tokushima Graduate School
Miyoshi, Takanori Department of Oncological and Regenerative Surgery, Institute of Health Bioscience, The University of Tokushima Graduate School
Umemoto, Atsushi Department of Oncological and Regenerative Surgery, Institute of Health Bioscience, The University of Tokushima Graduate School
Tangoku, Akira Department of Oncological and Regenerative Surgery, Institute of Health Bioscience, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
esophageal cancer
chemotherapy
lung metastasis
Content Type
Journal Article
Description
A 55-year-old-male patient underwent subtotal esophagectomy for esophageal cancer (pT1b, N0, M0, stage II) in April 2005. The patient received postoperative chemotherapy (docetaxel 40 mg/body, 5-fluorouracil 750 mg/body, cisplatin 10 mg/body : administered every 4 weeks) for 3 months. Six months postoperatively, routine follow up CT demonstrated multiple metastatic tumors in the bilateral lungs. Under the diagnosis of multiple lung metastases, the patient was hospitalized and received intensive chemotherapy with docetaxel 40 mg/ week (day 1), 5-fluorouracil 500 mg/ day (days 1-5), cisplatin 10 mg/ day (days 1-5). After two weeks administration, the patient eagerly hoped for outpatient treatment. The treatment was changed to outpatient chemotherapy with S-1 100 mg/ day (continuous administration for 3 weeks followed by rest for 1 week) and cisplatin 20 mg/ every week. The treatment enabled the patient to keep working. Follow up CT showed disappearance of all tumors two months after TS-1/cisplatin chemotherapy. There were no obvious signs of recurrence 5 months after chemotherapy. The S-1/cisplatin therapy in the outpatient was thought to be one of the effective treatments in maintaining quality of life for the patient.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
53
Issue
3-4
Start Page
321
End Page
324
Sort Key
321
Published Date
2006-08
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital
Medical Sciences