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ID 113452
Author
Oonishi, Akinori Kyoto University
Kuroda, Yusuke Kyoto University
Harada, Shingo Kyoto University
Kiyama, Hiroki Kyoto University
Yamaoka, Yousuke Kyoto University
Takasu, Kiyosei Kyoto University
Keywords
Organocatalysis
Desymmetrization
Acid anhydride
Chiral phosphoric acid
Chiral Brønsted acid
Content Type
Journal Article
Description
Asymmetric desymmetrization of σ-symmetric acid anhydrides was achieved with chiral phosphoric acid as a Brønsted acid catalyst. The key of success was finding of benzhydrol and 2,2-diphenylethanol as the nucleophiles of choice. The corresponding half esters were obtained in good yields with high selectivity.
Journal Title
Tetrahedron Letters
ISSN
00404039
NCID
AA00861801
AA11539822
Publisher
Elsevier
Volume
57
Issue
36
Start Page
4098
End Page
4100
Published Date
2016-07-30
Rights
© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Author
departments
Pharmaceutical Sciences