ID | 113938 |
Author |
Nakao, Michiyasu
Tokushima University
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Tsuji, Shunsuke
Tokushima University
Kitaike, Syuji
Tokushima University
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Sano, Shigeki
Tokushima University
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Keywords | erythrochelin
rhodotorulic acid
siderophore
2,5-diketopiperazine
electrospray ionization mass spectrometry
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Content Type |
Journal Article
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Description | Erythrochelin, a hydroxamate-type siderophore produced by Saccharopolyspora erythraea, is synthesized for the first time. A key building block of erythrochelin containing the 2,5-diketopiperazine ring is prepared by intramolecular cyclization of the corresponding dipeptide precursor derived from two kinds of protected δ-N-hydroxy-L-ornithines. Consecutive condensation of the building block with protected D-serine and protected δ-N-hydroxy-D-ornithine, followed by deprotection, furnishes erythrochelin.
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Journal Title |
Synthesis
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ISSN | 00397881
1437210X
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NCID | AA00855740
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Publisher | Georg Thieme Verlag Stuttgart
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Volume | 48
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Issue | 23
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Start Page | 4149
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End Page | 4154
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Published Date | 2016-08-24
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Author
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departments |
Pharmaceutical Sciences
Technical Support Department
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