| ID | 116231 |
| Author |
Lee, Sanghoon
Tokushima University|Simon Fraser University
Tanaka, Naonobu
Tokushima University
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Takahashi, Sakura
Tokushima University
Kim, Sang-Yong
Health Sciences University of Hokkaido
Kojoma, Mareshige
Health Sciences University of Hokkaido
Itoh, Kohji
Tokushima University
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Kobayashi, Jun’ichi
Hokkaido University
|
| Keywords | agesasines
bromopyrrole alkaloid
marine sponge
Agelas
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| Content Type |
Journal Article
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| Description | Exploration for specialized metabolites of Okinawan marine sponges Agelas spp. resulted in the isolation of five new bromopyrrole alkaloids, agesasines A (1) and B (2), 9-hydroxydihydrodispacamide (3), 9-hydroxydihydrooroidin (4), and 9E-keramadine (5). Their structures were elucidated on the basis of spectroscopic analyses. Agesasines A (1) and B (2) were assigned as rare bromopyrrole alkaloids lacking an aminoimidazole moiety, while 3–5 were elucidated to be linear bromopyrrole alkaloids with either aminoimidazolone, aminoimidazole, or N-methylated aminoimidazole moieties.
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| Journal Title |
Marine Drugs
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| ISSN | 16603397
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| Publisher | MDPI
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| Volume | 18
|
| Issue | 9
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| Start Page | 455
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| Published Date | 2020-08-30
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| Rights | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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| EDB ID | |
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
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| TextVersion |
Publisher
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| departments |
Bioscience and Bioindustry
Pharmaceutical Sciences
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