ID | 116570 |
Title Alternative | Diagnostic utility of FeNO for CTVA
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Author |
Hanibuchi, Masaki
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Tokushima University Educator and Researcher Directory
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Mitsuhashi, Atsushi
Tokushima University
Tokushima University Educator and Researcher Directory
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Kajimoto, Tatsuya
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Saijo, Atsuro
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
KAKEN Search Researchers
Kitagawa, Tetsuya
Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Tokushima University Educator and Researcher Directory
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Keywords | chest tightness variant asthma
fractional exhaled nitric oxide
biomarker
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Content Type |
Journal Article
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Description | A 50-year-old woman was referred to our hospital for further examination of severe constricting pain at the right-side dominant anterior chest. She had medical history of outgrown childhood asthma and allergies to several animals. Chest auscultation revealed no wheezes, rhonchi and other crackles. Laboratory findings showed an eosinophilia and an elevation of total immunoglobulin E. The results of an electrocardiogram, a chest X-ray and a chest CT were unremarkable. A fractional exhaled nitric oxide value remarkably elevated, but the abnormalities in pulmonary function test were modest. Her chest pain was ameliorated after inhaling procaterol. Based on these findings, a diagnosis of chest tightness variant asthma was formulated, and we started treatment with inhaled corticosteroid / long acting β2 agonist. At two-weeks after treatment, her symptom markedly improved and a fractional exhaled nitric oxide value decreased, which led to a definitive diagnosis of chest tightness variant asthma. A fractional exhaled nitric oxide value further decreased to the normal range in consistent with symptom disappearance at 10-months after treatment, indicating the usefulness of fractional exhaled nitric oxide as a promising marker for the diagnosis and clinical improvement of chest tightness variant asthma.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA11166929
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Publisher | Tokushima University Faculty of Medicine
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Volume | 68
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Issue | 3-4
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Start Page | 389
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End Page | 392
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Sort Key | 389
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Published Date | 2021-08
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DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
Medical Sciences
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