ID | 117242 |
Title Alternative | Sedentary Time and All-Cause Mortality
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Author |
Koyama, Teruhide
Kyoto Prefectural University of Medicine
Ozaki, Etsuko
Kyoto Prefectural University of Medicine
Kuriyama, Nagato
Kyoto Prefectural University of Medicine|Shizuoka Graduate University of Public Health
Tomida, Satomi
Kyoto Prefectural University of Medicine
Yoshida, Tamami
Kyoto Prefectural University of Medicine
Uehara, Ritei
Kyoto Prefectural University of Medicine
Tanaka, Keitaro
Saga University
Hara, Megumi
Saga University
Hishida, Asahi
Nagoya University
Okada, Rieko
Nagoya University
Kubo, Yoko
Nagoya University
Oze, Isao
Aichi Cancer Center Research Institute
Koyanagi, Yuriko N.
Aichi Cancer Center Research Institute
Mikami, Haruo
Chiba Cancer Center Research Institute
Nakamura, Yohko
Chiba Cancer Center Research Institute
Shimoshikiryo, Ippei
Kagoshima University
Takezaki, Toshiro
Kagoshima University
Suzuki, Sadao
Nagoya City University
Otani, Takahiro
Nagoya City University
Kuriki, Kiyonori
University of Shizuoka
Takashima, Naoyuki
Kindai University|Shiga University of Medical Science
Kadota, Aya
Shiga University of Medical Science
Arisawa, Kokichi
Tokushima University
Tokushima University Educator and Researcher Directory
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Katsuura-Kamano, Sakurako
Tokushima University
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Ikezaki, Hiroaki
Kyushu University
Murata, Masayuki
Kyushu University
Takeuchi, Kenji
Nagoya University
Wakai, Kenji
Nagoya University
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Keywords | all-cause mortality
diabetes mellitus
dyslipidemia
hypertension
sedentary time
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Content Type |
Journal Article
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Description | BACKGROUND: This study aimed to determine the association between sedentary time and mortality with regard to leisure‐time physical activity with or without cardiometabolic diseases such as hypertension, dyslipidemia, and diabetes mellitus.
METHODS AND RESULTS: Using data from the J‐MICC (Japan Multi‐Institutional Collaborative Cohort) Study, 64 456 participants (29 022 men, 35 434 women) were analyzed. Hazard ratios (HRs) and 95% CIs were used to characterize the relative risk of all‐cause mortality to evaluate its association with sedentary time (categorical variables: <5, 5 to <7, 7 to <9, ≥9 h/d and 2‐hour increments in exposure) according to the self‐reported hypertension, dyslipidemia, and diabetes mellitus using a Cox proportional hazards model. A total of 2257 participants died during 7.7 years of follow‐up. The corresponding HRs for each 2‐hour increment in sedentary time among participants with all factors, no factors, hypertension, dyslipidemia, and diabetes mellitus were 1.153 (95% CI, 1.114–1.194), 1.125 (95% CI, 1.074–1.179), 1.202 (95% CI, 1.129–1.279), 1.176 (95% CI, 1.087–1.273), and 1.272 (95% CI, 1.159–1.396), respectively. Furthermore, when analyzed according to the combined different factors (hypertension, dyslipidemia, and diabetes mellitus), HRs increased with each additional factor, and participants reporting all 3 conditions had the highest HR of 1.417 (95% CI, 1.162–1.728) independently of leisure‐time metabolic equivalents. CONCLUSIONS: The association between sedentary time and increased mortality is stronger among patients with hypertension, dyslipidemia, and diabetes mellitus regardless of leisure‐time physical activity in a large Japanese population. |
Journal Title |
Journal of the American Heart Association
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ISSN | 20479980
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Publisher | The American Heart Association|Wiley
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Volume | 10
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Issue | 13
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Start Page | e018293
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Published Date | 2021-06-14
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Rights | This is an open access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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language |
eng
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departments |
Medical Sciences
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